You are in the accessibility menu

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/72800
Title: 
Avaliação do estresse oxidativo no sangue de consumidores habituais de suco de laranja
Other Titles: 
Evaluation of serum oxidative stress in regular consumers of orange juice
Author(s): 
Institution: 
Universidade Estadual Paulista (UNESP)
ISSN: 
1808-4532
Abstract: 
  • Two biomarkers of oxidative stress were evaluated in healthy volunteers treated with daily doses of orange juice that is well known source of vitamin C and citric flavanones, which have been associated with antioxidant, anti-inflammatory and hypolipidemic effects. The antioxidant capacity in the blood serum was evaluated by studying the scavenging of 2,2'-diphenyl-1-picrylhydrazyl (DPPH) free radical, and also lipid peroxidation was evaluated by the thiobarbituric acid reacting substances (TBARS) assay. The results have shown that the regular consumption of orange juice increased 150% and 200% the serum antioxidant capacity for women and men respectively, but it was no significant change in the serum lipid peroxidation. In conclusion, the increase of flavonones and vitamin C in the body due to the regular intake of orange juice expressively improved the antioxidant capacity, but without significant effect on the lipid peroxidation.
  • Dois biomarcadores do estresse oxidativo foram avaliados em indivíduos saudáveis que receberam doses diárias de suco de laranja, notadamente uma fonte de vitamina C e de flavanonas, que têm sido associadas aos efeitos antioxidante, anti-inflamatório e hipolipidêmico. A capacidade antioxidante do soro sanguíneo foi avaliada através da redução do radical 2,2-difenil-1-picril-hidrazila (DPPH) e a peroxidação lipídica foi avaliada pela presença de substâncias reativas ao ácido tiobarbitúrico (TBARS). Os resultados mostraram que após o período de suplementação com o suco de laranja houve um aumento 150% na capacidade antioxidante no soro das mulheres e 200% no soro dos homens (p<0,001), mas não houve alteração na peroxidação lipídica no sangue dos voluntários. Concluindo, o aumento das reservas de flavanonas e de vitamina C, decorrente da ingestão regular de suco de laranja, melhorou expressivamente a capacidade antioxidante no sangue, sem, entretanto, apresentar efeito sobre a peroxidação lipídica.
Issue Date: 
14-Nov-2011
Citation: 
Revista de Ciencias Farmaceuticas Basica e Aplicada, v. 32, n. 2, p. 275-279, 2011.
Time Duration: 
275-279
Keywords: 
  • Antioxidant activity
  • Citric flavonoids
  • Lipid peroxidation
  • Orange juice
  • Oxidative stress
  • Vitamin C
  • 1,1 diphenyl 2 picrylhydrazyl
  • ascorbic acid
  • flavanone derivative
  • thiobarbituric acid reactive substance
  • antiinflammatory activity
  • antioxidant activity
  • blood analysis
  • dietary intake
  • female
  • human
  • human experiment
  • lipid peroxidation
  • male
  • normal human
  • orange juice
  • oxidative stress
Source: 
http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/1417
URI: 
Access Rights: 
Acesso aberto
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/72800
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.
 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.