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http://acervodigital.unesp.br/handle/11449/73011
- Title:
- Participação da via alfa-2 adrenérgica no controle da secreção do hormônio do crescimento no período prépúbere em novilhas da raça Nelore
- Participation of the pathway alfa-2: Adrenergic in the control of growth hormone secretion in the pre-puberty period of the Nellore heifers
- Universidade Estadual Paulista (UNESP)
- Agência Paulista de Tecnologia dos Agronegócios (APTA)
- 1413-9596
- 1678-4456
- This study investigated GH secretion after clonidine (alpha-2 adrenergic agonist) treatment in pre-pubertal Nelore heifers. Clonidine (10 mg/kg, IV, 15 min samples for 4 h) was administrated in the same Nelore heifers at eight (n = 4), 12 (n = 5) and 15 (n = 4) months of age. The GH concentration was measured by radioimmunoassay (sensivity = 0.25 ng/mL, CV = 16%). At eight months, clonidine increased GH average concentration, total area of peaks, the total area of GH secretion and increased peak amplitude and reduced time to onset of peak (P < 0.05). At 15 months, the administration of clonidine increased the GH average concentration and at 12 months the increased occurred only in restricted intervals (P < 0.05). Clonidine injection stimulated GH secretion in prepubertal heifers and this effect was more evident in Nelore heifers at eight months compared to 12 and 15 months of age.
- 1-Dec-2011
- Brazilian Journal of Veterinary Research and Animal Science, v. 48, n. 4, p. 325-331, 2011.
- 325-331
- Clonidine
- GH
- Nelore
- Prepubertal
- http://www.revistas.usp.br/bjvras/article/view/34397
- Acesso aberto
- outro
- http://repositorio.unesp.br/handle/11449/73011
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