Intermediate reactive oxygen and nitrogen from macrophages induced by Brazilian lichens

Santos, Lourdes Campaner dos; Honda, N. K.; Carlos, I. Z.; Vilegas, Wagner

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/7554

Title:

Intermediate reactive oxygen and nitrogen from macrophages induced by Brazilian lichens

Author(s):

Institution:

Universidade Estadual Paulista (UNESP)
Universidade Federal de Mato Grosso do Sul (UFMS)

ISSN:

0367-326X

Abstract:

The activity of ten compounds isolated from Brazilian lichen over the release of hydrogen peroxide and nitric oxide was evaluated in the culture of peritoneal macrophage cells from mice. Salazinic, secalonic A and fumarprotocetraric acids were the compounds that induced the greatest release of H2O2, whereas 12R-usnic and diffractaic acids induced the release of NO. These results indicate that lichen products have potential immunological modulating activities. (C) 2004 Elsevier B.V. All rights reserved.

Issue Date:

1-Jul-2004

Citation:

Fitoterapia. Amsterdam: Elsevier B.V., v. 75, n. 5, p. 473-479, 2004.

Time Duration:

473-479

Publisher:

Elsevier B.V.

Keywords:

lichens
macrophages
peroxide hydrogen
nitric oxide

Source:

http://dx.doi.org/10.1016/j.fitote.2004.04.002

URI:

Access Rights:

Acesso restrito

Type:

outro

Source:

http://repositorio.unesp.br/handle/11449/7554

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