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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/7608
Title: 
Development and validation of a nonaqueous titration with perchloric acid to determine sparfloxacin in tablets
Author(s): 
Institution: 
  • Universidade Estadual Paulista (UNESP)
  • Universidade Federal do Rio Grande do Sul (UFRGS)
ISSN: 
0939-6411
Abstract: 
A simple, rapid and inexpensive method for the determination of sparfloxacin in tablets is described. The procedure is based on the use of volumetric dosage in a nonaqueous medium in glacial acetic acid with 0.1 M perchloric acid. The method validation yielded good results and included precision and accuracy. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay. (C) 2001 Elsevier B.V. B.V. All rights reserved.
Issue Date: 
1-Sep-2001
Citation: 
European Journal of Pharmaceutics and Biopharmaceutics. Amsterdam: Elsevier B.V., v. 52, n. 2, p. 227-229, 2001.
Time Duration: 
227-229
Publisher: 
Elsevier B.V.
Keywords: 
  • fluoroquinolone
  • nonaqueous titration
  • pharmaceutical analysis
  • sparfloxacin
Source: 
http://dx.doi.org/10.1016/S0939-6411(01)00177-1
URI: 
Access Rights: 
Acesso restrito
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/7608
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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