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http://acervodigital.unesp.br/handle/11449/8769- Title:
- Vibrational and Thermal Properties of Crystalline Topiramate
- Universidade Federal do Ceará (UFC)
- Univ Reg Cariri
- Universidade Estadual Paulista (UNESP)
- Universidade Estadual de Campinas (UNICAMP)
- 0103-5053
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
- Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico (FUNCAP)
- CENAPAD-SP (project 373)
- Topiramate, a powerful anticonvulsant drug, was investigated by X-ray diffractometry, FT-Raman, FT-IR, TGA and DTA techniques as well as by DFT calculations. From this study it was possible to tentatively assign most of the normal vibrational modes of the crystal. Thermal analysis from room temperature to 900 degrees C shows that the material does not present any structural phase transition and that the decomposition occurs in a two-step exothermic process.
- 1-Jan-2008
- Journal of The Brazilian Chemical Society. São Paulo: Soc Brasileira Quimica, v. 19, n. 8, p. 1607-1613, 2008.
- 1607-1613
- Soc Brasileira Quimica
- organic crystals
- vibrational spectra
- X-ray diffraction
- thermodynamic properties
- http://dx.doi.org/10.1590/S0103-50532008000800022
- Acesso aberto
- outro
- http://repositorio.unesp.br/handle/11449/8769
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