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http://acervodigital.unesp.br/handle/11449/10620
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DC Field | Value | Language |
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dc.contributor.author | Rossi, Denise M | - |
dc.contributor.author | Valenti, Vitor Engrácia | - |
dc.contributor.author | Navega, Marcelo Tavella | - |
dc.date.accessioned | 2014-05-20T13:31:10Z | - |
dc.date.available | 2014-05-20T13:31:10Z | - |
dc.date.issued | 2011-01-01 | - |
dc.identifier | http://dx.doi.org/10.1590/S1807-59322011000900019 | - |
dc.identifier.citation | Clinics. Faculdade de Medicina / USP, v. 66, n. 9, p. 1615-1619, 2011. | - |
dc.identifier.issn | 1807-5932 | - |
dc.identifier.uri | http://hdl.handle.net/11449/10620 | - |
dc.description.abstract | OBJECTIVES: We investigated the effects of chronic (eight weeks) low-to moderate-intensity swimming training on thermal pain sensitivity in streptozotocin-induced diabetic female rats. METHODS: Female Wistar rats (n = 51) were divided into the following groups: trained streptozotocin-induced diabetic rats [hyperglycemic trained (HT)], sedentary streptozotocin-induced diabetic rats [hyperglycemic sedentary (HS)], normoglycemic trained rats (NT) and normoglycemic sedentary rats (NS). Diabetes was induced by a single injection of streptozotocin (50 mg/kg, i.p.). One day after the last exercise protocol (60 min/day, five days/week for eight weeks) in the trained groups or after water stress exposure (ten min/twice a week) in the sedentary groups, the rats were subjected to a hot plate test. RESULTS: After eight weeks of swimming training, streptozotocin-induced diabetic rats presented a significantly lower body mass (trained: 219.5±29 g, sedentary: 217.8±23 g) compared with the normoglycemic groups (trained: 271±24 g, sedentary: 275.7±32 g). Interestingly, we did not find differences in blood glucose levels (mg/dl) between the trained and sedentary groups of the hyperglycemic or normoglycemic rats (HT: 360.2±6.6, HS: 391.7±6.7, NT: 83.8±14.0, NS: 77.5±10.1). In the hot plate test, the rats from the HT group presented a significantly lower latency than the other rats (HT: 11.7±7.38 s, HS: 7.02±7.38 s, NT: 21.21±7.64 s, NS: 22.82±7.82 s). CONCLUSION: Low-to-moderate swimming training for a long duration reduces thermal hyperalgesia during a hot plate test in streptozotocin-induced diabetic female rats. | en |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
dc.format.extent | 1615-1619 | - |
dc.language.iso | eng | - |
dc.publisher | Universidade de São Paulo (USP), Faculdade de Medicina | - |
dc.source | SciELO | - |
dc.subject | Diabetes mellitus | en |
dc.subject | Diabetic neuropathy | en |
dc.subject | Pain sensitivity | en |
dc.subject | Physical exercise | en |
dc.subject | Swimming training | en |
dc.subject | Hot plate test | en |
dc.title | Exercise training attenuates acute hyperalgesia in streptozotocin-induced diabetic female rats | en |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.contributor.institution | Universidade de São Paulo (USP) | - |
dc.description.affiliation | UNESP Faculdade de Filosofia e Ciência Departamento de Educação Especial | - |
dc.description.affiliation | Universidade São Paulo Faculdade de Medicina Departamento de Patologia | - |
dc.description.affiliationUnesp | UNESP Faculdade de Filosofia e Ciência Departamento de Educação Especial | - |
dc.identifier.doi | 10.1590/S1807-59322011000900019 | - |
dc.identifier.scielo | S1807-59322011000900019 | - |
dc.identifier.wos | WOS:000297498400019 | - |
dc.rights.accessRights | Acesso aberto | - |
dc.identifier.file | S1807-59322011000900019.pdf | - |
dc.relation.ispartof | Clinics | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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