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DC Field | Value | Language |
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dc.contributor.author | Ribeiro, Onesimo D. | - |
dc.contributor.author | Abreu, Luiz Carlos de | - |
dc.contributor.author | Valenti, Vitor Engrácia | - |
dc.contributor.author | Cisternas, Jose Raul | - |
dc.contributor.author | Saletti, Deise | - |
dc.contributor.author | Lima, Carla J. B. | - |
dc.contributor.author | Silvestre, Diego N. | - |
dc.contributor.author | Godoy, Ivan R. B. | - |
dc.contributor.author | Mello, Luiz G. M. | - |
dc.contributor.author | Nascimento, Vania B. | - |
dc.contributor.author | Martins, Lourdes C. | - |
dc.date.accessioned | 2014-05-20T13:31:34Z | - |
dc.date.available | 2014-05-20T13:31:34Z | - |
dc.date.issued | 2011-12-01 | - |
dc.identifier | http://dx.doi.org/10.5897/AJPP11.486 | - |
dc.identifier.citation | African Journal of Pharmacy and Pharmacology. Victoria Island: Academic Journals, v. 5, n. 23, p. 2598-2604, 2011. | - |
dc.identifier.issn | 1996-0816 | - |
dc.identifier.uri | http://hdl.handle.net/11449/10760 | - |
dc.description.abstract | We aimed to compare the analgesic efficacy of the caudal administration of a combination of preservative free S-ketamine or clonidine with bupivacaine in children. The study included 51 children aged between 3 and 8 years old and physical status between I and II according to: American Society of Anesthesiologist. They were randomly divided into three groups: Group B - bupivacaine 0.25%, 0.75 ml/kg without adrenaline; Group C - bupivacaine 0.25%, 0.75 ml/kg without adrenaline and clonidine 1 mu g/kg and; Group K - bupivacaine 0.25%, 0.75 ml/kg without adrenaline and S-ketamine 0.5 mg/kg without conservative. In this study, medication was not used before anesthesia. The evaluation of postoperative analgesia was accomplished through the pain scale of Ouch, the motor blockade assessed by modified Bromage scale and the level of sedation through the three-point scale. The combination of caudal S-ketamine and clonidine with bupivacaine prolonged the duration of postoperative analgesia (p < 0.05) compared to bupivacaine alone. Regarding hemodynamic parameters, bupivacaine associated with clonidine (C) and bupivacaine associated with S-ketamine (K) groups presented diastolic blood pressure changes in the postoperative period. Respiratory rate, regardless of group, showed significant differences over time (p < 0.05). The studied groups showed non significant changes in the degree of motor blockade and sedation score and we observed no clinical significant side effects. S-ketamine and clonidine associated with bupivacaine prolongs postoperative analgesia without clinically significant side effects. | en |
dc.description.sponsorship | Nucleo de Estudos, Pesquisas e Assessoria a Saúde da Faculdade de Medicina do ABC (NEPAS-FMABC) | - |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
dc.format.extent | 2598-2604 | - |
dc.language.iso | eng | - |
dc.publisher | Academic Journals | - |
dc.source | Web of Science | - |
dc.subject | Pediatric assistants | en |
dc.subject | anesthesia | en |
dc.subject | analgesia | en |
dc.subject | epidural | en |
dc.subject | anesthesia | en |
dc.subject | caudal | en |
dc.subject | anesthetics | en |
dc.title | Comparison between S-ketamine and clonidine in caudal analgesia | en |
dc.type | outro | - |
dc.contributor.institution | Fac Med ABC | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.contributor.institution | Disciplina Saúde Colet | - |
dc.description.affiliation | Fac Med ABC, Disciplina Anestesiol, Santo Andre, SP, Brazil | - |
dc.description.affiliation | Fac Med ABC, Dept Morfol & Fisiol, Santo Andre, SP, Brazil | - |
dc.description.affiliation | Univ Estadual Paulista, Fac Filosofia & Ciencias, Dept Fonoaudiol, Marilia, SP, Brazil | - |
dc.description.affiliation | Disciplina Saúde Colet, Santo Candre, SP, Brazil | - |
dc.description.affiliation | Fac Med ABC, Santo Candre, SP, Brazil | - |
dc.description.affiliationUnesp | Univ Estadual Paulista, Fac Filosofia & Ciencias, Dept Fonoaudiol, Marilia, SP, Brazil | - |
dc.identifier.doi | 10.5897/AJPP11.486 | - |
dc.identifier.wos | WOS:000299677800010 | - |
dc.rights.accessRights | Acesso aberto | - |
dc.identifier.file | WOS000299677800010.pdf | - |
dc.relation.ispartof | African Journal of Pharmacy and Pharmacology | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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