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http://acervodigital.unesp.br/handle/11449/112170
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DC Field | Value | Language |
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dc.contributor.author | Rocha, V. A. | - |
dc.contributor.author | Frazao, R. | - |
dc.contributor.author | Campos, L. M. G. | - |
dc.contributor.author | Mello, P. | - |
dc.contributor.author | Donato, J. | - |
dc.contributor.author | Cruz-Rizzolo, R. J. | - |
dc.contributor.author | Nogueira, M. I. | - |
dc.contributor.author | Pinato, Luciana | - |
dc.date.accessioned | 2014-12-03T13:10:29Z | - |
dc.date.accessioned | 2016-10-25T20:10:35Z | - |
dc.date.available | 2014-12-03T13:10:29Z | - |
dc.date.available | 2016-10-25T20:10:35Z | - |
dc.date.issued | 2014-01-16 | - |
dc.identifier | http://dx.doi.org/10.1016/j.brainres.2013.10.037 | - |
dc.identifier.citation | Brain Research. Amsterdam: Elsevier Science Bv, v. 1543, p. 65-72, 2014. | - |
dc.identifier.issn | 0006-8993 | - |
dc.identifier.uri | http://hdl.handle.net/11449/112170 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/112170 | - |
dc.description.abstract | The suprachiasmatic nucleus (SCN), which is the main circadian biological clock in mammals, is composed of multiple cells that function individually as independent oscillators to express the self-sustained mRNA and protein rhythms of the so-called clock genes. Knowledge regarding the presence and localization of the proteins and neuroactive substances of the SCN are essential for understanding this nucleus and for its successful manipulation. Although there have been advances in the investigation of the intrinsic organization of the SCN in rodents, little information is available in diurnal species, especially in primates. This study, which explores the pattern of expression and localization of PER2 protein in the SCN of capuchin monkey, evaluates aspects of the circadian system that are common to both primates and rodents. Here, we showed that PER2 protein immunoreactivity is higher during the light phase. Additionally, the complex organization of cells that express vasopressin, vasoactive intestinal polypeptide, neuron-specific nuclear protein, calbindin and calretinin in the SCN, as demonstrated by their immunoreactivity, reveals an intricate network that may be related to the similarities and differences reported between rodents and primates in the literature. (C) 2013 Elsevier B.V. All rights reserved. | en |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
dc.format.extent | 65-72 | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier B.V. | - |
dc.source | Web of Science | - |
dc.subject | Biological rhythms | en |
dc.subject | Diurnal monkey | en |
dc.subject | Neuroanatomy | en |
dc.subject | Per2 | en |
dc.title | Intrinsic organization of the suprachiasmatic nucleus in the capuchin monkey | en |
dc.type | outro | - |
dc.contributor.institution | Universidade de São Paulo (USP) | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.description.affiliation | Univ Sao Paulo, Inst Biomed Sci, Dept Anat, BR-05508 Sao Paulo, Brazil | - |
dc.description.affiliation | Sao Paulo State Univ, Dept Speech Language & Hearing Therapy, BR-17515901 Marilia, SP, Brazil | - |
dc.description.affiliation | Univ Sao Paulo, Inst Biomed Sci, Dept Physiol & Biophys, BR-05508 Sao Paulo, Brazil | - |
dc.description.affiliation | Sao Paulo State Univ Aracatuba, Dept Basic Sci, Aracatuba, SP, Brazil | - |
dc.description.affiliationUnesp | Sao Paulo State Univ, Dept Speech Language & Hearing Therapy, BR-17515901 Marilia, SP, Brazil | - |
dc.description.affiliationUnesp | Sao Paulo State Univ Aracatuba, Dept Basic Sci, Aracatuba, SP, Brazil | - |
dc.description.sponsorshipId | FAPESP: 08/53689-8 | - |
dc.identifier.doi | 10.1016/j.brainres.2013.10.037 | - |
dc.identifier.wos | WOS:000330491300008 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Brain Research | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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