You are in the accessibility menu

Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorla Serrana, Daniel Garcia de-
dc.contributor.authorMareco, Edson A.-
dc.contributor.authorJohnston, Ian A.-
dc.identifier.citationGenome Biology And Evolution. Oxford: Oxford Univ Press, v. 6, n. 4, p. 981-987, 2014.-
dc.description.abstractTeleost fish underwent whole-genome duplication around 450 Ma followed by diploidization and loss of 80-85% of the duplicated genes. To identify a deep signature of this teleost-specific whole-genome duplication (TSGD), we searched for duplicated genes that were systematically and uniquely retained in one or other of the superorders Ostariophysi and Acanthopterygii. TSGD paralogs comprised 17-21% of total gene content. Some 2.6% (510) of TSGD paralogs were present as pairs in the Ostariophysi genomes of Danio rerio (Cypriniformes) and Astyanax mexicanus (Characiformes) but not in species from four orders of Acanthopterygii (Gasterosteiformes, Gasterosteus aculeatus; Tetraodontiformes, Tetraodon nigroviridis; Perciformes, Oreochromis niloticus; and Beloniformes, Oryzias latipes) where a single copy was identified. Similarly, 1.3% (418) of total gene number represented cases where TSGD paralogs pairs were systematically retained in the Acanthopterygian but conserved as a single copy in Ostariophysi genomes. We confirmed the generality of these results by phylogenetic and synteny analysis of 40 randomly selected linage-specific paralogs (LSPs) from each superorder and completed with the transcriptomes of three additional Ostariophysi species (Ictalurus punctatus [Siluriformes], Sinocyclocheilus species [Cypriniformes], and Piaractus mesopotamicus [Characiformes]). No chromosome bias was detected in TSGD paralog retention. Gene ontology (GO) analysis revealed significant enrichment of GO terms relative to the human GO SLIM database for growth, Cell differentiation, and Embryo development in Ostariophysi and for Transport, Signal Transduction, and Vesicle mediated transport in Acanthopterygii. The observed patterns of paralog retention are consistent with different diploidization outcomes having contributed to the evolution/diversification of each superorder.en
dc.description.sponsorshipMarine Alliance for Science and Technology for Scotland pooling initiative-
dc.description.sponsorshipScottish Funding Council-
dc.publisherOxford University Press-
dc.sourceWeb of Science-
dc.subjectfish evolutionen
dc.subjectgene lossen
dc.subjectwhole-genome duplicationen
dc.titleSystematic Variation in the Pattern of Gene Paralog Retention between the Teleost Superorders Ostariophysi and Acanthopterygiien
dc.contributor.institutionUniv St Andrews-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniv St Andrews, Sch Biol, Scottish Oceans Inst, St Andrews KY16 9AJ, Fife, Scotland-
dc.description.affiliationUNESP Univ Estadual Paulista, Inst Biosci Botucatu, Dept Morphol, Sao Paulo, Brazil-
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Inst Biosci Botucatu, Dept Morphol, Sao Paulo, Brazil-
dc.description.sponsorshipIdScottish Funding CouncilHR09011-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofGenome Biology And Evolution-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.