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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/11437
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dc.contributor.authorCamargo, Carlos Henrique-
dc.contributor.authorBruder-Nascimento, Ariane-
dc.contributor.authorMondelli, Alessandro Lia-
dc.contributor.authorMontelli, Augusto Cezar-
dc.contributor.authorSadatsune, Terue-
dc.date.accessioned2014-05-20T13:33:24Z-
dc.date.available2014-05-20T13:33:24Z-
dc.date.issued2011-09-01-
dc.identifierhttp://dx.doi.org/10.1590/S1413-86702011000500011-
dc.identifier.citationBrazilian Journal of Infectious Diseases. Salvador: Contexto, v. 15, n. 5, p. 478-481, 2011.-
dc.identifier.issn1413-8670-
dc.identifier.urihttp://hdl.handle.net/11449/11437-
dc.description.abstractPhenotypic and genotypic SPM and IMP metallo-beta-lactamases (MBL) detection and also the determination of minimal inhibitory concentrations (MIC) to imipenem, meropenem and ceftazidime were evaluated in 47 multidrug-resistant Pseudomonas aeruginosa isolates from clinical specimens. Polymerase chain reaction detected 14 positive samples to either bla(SPM) or bla(IMP) genes, while the best phenotypic assay (ceftazidime substrate and mercaptopropionic acid inhibitor) detected 13 of these samples. Imipenem, meropenem and ceftazidime MICs were higher for MBL positive compared to MBL negative isolates. We describe here the SPM and IMP MBL findings in clinical specimens of P. aeruginosa from the University Hospital of Botucatu Medical School, São Paulo, Brazil, that reinforce local studies showing the high spreading of bla(SPM) and bla(IMP) genes among Brazilian clinical isolates.en
dc.format.extent478-481-
dc.language.isoeng-
dc.publisherContexto-
dc.sourceWeb of Science-
dc.subjectPseudomonas aeruginosaen
dc.subjectdrug resistanceen
dc.subjectbacterialen
dc.subjectcarbapenemsen
dc.subjectmetalloproteinsen
dc.subjectpolymerase chain reactionen
dc.titleDetection of SPM and IMP metallo-beta-lactamases in clinical specimens of Pseudomonas aeruginosa from a Brazilian public tertiary hospitalen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniv Estatual Paulista UNESP, Botucatu, SP, Brazil-
dc.description.affiliationUNESP, Botucatu, SP, Brazil-
dc.description.affiliationUnespUniv Estatual Paulista UNESP, Botucatu, SP, Brazil-
dc.description.affiliationUnespUNESP, Botucatu, SP, Brazil-
dc.identifier.scieloS1413-86702011000500011-
dc.identifier.wosWOS:000295936600011-
dc.rights.accessRightsAcesso aberto-
dc.identifier.fileS1413-86702011000500011-en.pdf-
dc.relation.ispartofBrazilian Journal of Infectious Diseases-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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