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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/116323
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dc.contributor.authorParedes, Mayte-
dc.contributor.authorPulcinelli, Sandra Helena-
dc.contributor.authorPeniche, Carlos-
dc.contributor.authorGoncalves, Vanessa-
dc.contributor.authorSantilli, Celso Valentim-
dc.date.accessioned2015-03-18T15:53:03Z-
dc.date.accessioned2016-10-25T20:24:31Z-
dc.date.available2015-03-18T15:53:03Z-
dc.date.available2016-10-25T20:24:31Z-
dc.date.issued2014-11-01-
dc.identifierhttp://dx.doi.org/10.1007/s10971-014-3314-8-
dc.identifier.citationJournal Of Sol-gel Science And Technology. Dordrecht: Springer, v. 72, n. 2, p. 233-238, 2014.-
dc.identifier.issn0928-0707-
dc.identifier.urihttp://hdl.handle.net/11449/116323-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/116323-
dc.description.abstractThe effect of chitosan addition on the structure and drug release properties of ureasil-polyethylene oxide (U-PEO) hybrid materials was examined. The hybrids and the blends were prepared by the sol-gel route and their structural features were characterized by infrared spectroscopy, differential scanning calorimetry, X-ray powder diffraction, and small angle X-ray scattering. The different characterization techniques revealed the formation of transparent, rubbery, flexible, water-insoluble, and low crystalline chitosan/(U-PEO hybrid) blends, which could easily dissolve pramoxine (used as a model drug). The results showed that the combined addition of chitosan and pramoxine improved the compatibility of the organic and inorganic components of the U-PEO matrix, and provided a means of tailoring the amount of drug released at steady state equilibrium.en
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.format.extent233-238-
dc.language.isoeng-
dc.publisherSpringer-
dc.sourceWeb of Science-
dc.subjectSol-gelen
dc.subjectHybrid materialsen
dc.subjectChitosanen
dc.subjectChitosan blendsen
dc.subjectDrug deliveryen
dc.titleChitosan/(ureasil-PEO hybrid) blend for drug deliveryen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionCtr Technol Applicat & Nucl Dev CEADEN-
dc.contributor.institutionUniv Havana-
dc.description.affiliationSao Paulo State Univ UNESP, Inst Chem, BR-14800900 Araraquara, SP, Brazil-
dc.description.affiliationCtr Technol Applicat & Nucl Dev CEADEN, Havana, Cuba-
dc.description.affiliationUniv Havana, Ctr Biomat BIOMAT, Havana, Cuba-
dc.description.affiliationUnespSao Paulo State Univ UNESP, Inst Chem, BR-14800900 Araraquara, SP, Brazil-
dc.identifier.doi10.1007/s10971-014-3314-8-
dc.identifier.wosWOS:000343131000005-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofJournal Of Sol-gel Science And Technology-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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