You are in the accessibility menu

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/116435
Full metadata record
DC FieldValueLanguage
dc.contributor.authorMatos, Bruno Mello de-
dc.contributor.authorAbreu Ribeiro, Zulene Eveline-
dc.contributor.authorBalducci, Ivan-
dc.contributor.authorFigueiredo, Maria Stella-
dc.contributor.authorBack-Brito, Graziella Nuernberg-
dc.contributor.authorMota, Adolfo Jose da-
dc.contributor.authorPellegrini Braga, Josefina Aparecida-
dc.contributor.authorKoga-Ito, Cristiane Yumi-
dc.date.accessioned2015-03-18T15:53:19Z-
dc.date.accessioned2016-10-25T20:24:47Z-
dc.date.available2015-03-18T15:53:19Z-
dc.date.available2016-10-25T20:24:47Z-
dc.date.issued2014-10-01-
dc.identifierhttp://dx.doi.org/10.1016/j.archoralbio.2014.05.014-
dc.identifier.citationArchives Of Oral Biology. Oxford: Pergamon-elsevier Science Ltd, v. 59, n. 10, p. 1042-1047, 2014.-
dc.identifier.issn0003-9969-
dc.identifier.urihttp://hdl.handle.net/11449/116435-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/116435-
dc.description.abstractBackground and objective: Sickle cell anaemia (SCA) is the most frequent haematological hereditary disease. Children with SCA are submitted to long-term prophylactic therapy with penicillin, but little is known about its impact on oral microflora. The aim of this study was to evaluate the oral microbial colonization of paediatric patients with SCA.Design: Forty children (4-11 yrs old) with SCA (genotype SS) under long-term prophylactic treatment with penicillin were included in the study. Age/gender-matched control group of healthy children was also included. Scores of dmft/DMFT (number of decayed (D), missing (M), or filled (F) teeth; dmft, for primary dentition; DMFT, for permanent dentition) were obtained and stimulated saliva was sampled. Salivary flow rate and buffering capacity were evaluated. Counts of microorganisms (mutans streptococci, lactobacilli and yeasts) were determined by plating method. Yeasts were identified by API 20C AUX and PCR.Results: Mean dmft/DMFT values were similar in the studied groups (SCA 2.13/1.60 and control 2.38/1.3). Although no significant differences between cariogenic microorganism counts were observed, significantly higher yeasts oral levels were observed in SCA group. Controls showed lower salivary buffering capacity. Candida albicans was the most frequently isolated species in both groups. Candida famata, Candida parapsilosis and Candida tropical is were also isolated from controls. Candida dubliniensis, Candida rugosa and Candida sphaerica were found only in SCA group.Conclusions: Based on the results, it could be concluded that paediatric patients with SCA showed significantly higher oral level of yeasts. Uncommon fungal species were found in SCA group. Similar caries prevalence and counts of lactobacilli and streptococci in relation to controls were observed. (C) 2014 Elsevier Ltd. All rights reserved.en
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.format.extent1042-1047-
dc.language.isoeng-
dc.publisherElsevier B.V.-
dc.sourceWeb of Science-
dc.subjectSickle cell anaemiaen
dc.subjectChildrenen
dc.subjectMouthen
dc.subjectCariesen
dc.subjectMicroorganismen
dc.titleOral microbial colonization in children with sickle cell anaemia under long-term prophylaxis with penicillinen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)-
dc.contributor.institutionUniv Fed Amazonas-
dc.description.affiliationUniv Estadual Paulista, UNESP, Inst Sci & Technol, BR-12245000 Sao Jose Dos Campos, SP, Brazil-
dc.description.affiliationUniv Fed Sao Paulo, Escola Paulista Med, Sao Paulo, Brazil-
dc.description.affiliationUniv Fed Amazonas, Programa Multiinst Posgrad Biotecnol Manaus, Manaus, AM, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, UNESP, Inst Sci & Technol, BR-12245000 Sao Jose Dos Campos, SP, Brazil-
dc.description.sponsorshipIdFAPESP: 07/58999-2-
dc.identifier.doi10.1016/j.archoralbio.2014.05.014-
dc.identifier.wosWOS:000341481700005-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofArchives Of Oral Biology-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.
 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.