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http://acervodigital.unesp.br/handle/11449/116707
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DC Field | Value | Language |
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dc.contributor.author | Altei, Wanessa F. | - |
dc.contributor.author | Picchi, Douglas G. | - |
dc.contributor.author | Abissi, Barbara M. | - |
dc.contributor.author | Giesel, Guilherme M. | - |
dc.contributor.author | Flausino, Otavio | - |
dc.contributor.author | Reboud-Ravaux, Michele | - |
dc.contributor.author | Verli, Hugo | - |
dc.contributor.author | Crusca, Edson | - |
dc.contributor.author | Silveira, Edilberto R. | - |
dc.contributor.author | Cilli, Eduardo M. | - |
dc.contributor.author | Bolzani, Vanderlan da Silva | - |
dc.date.accessioned | 2015-03-18T15:53:58Z | - |
dc.date.accessioned | 2016-10-25T20:27:52Z | - |
dc.date.available | 2015-03-18T15:53:58Z | - |
dc.date.available | 2016-10-25T20:27:52Z | - |
dc.date.issued | 2014-11-01 | - |
dc.identifier | http://dx.doi.org/10.1016/j.phytochem.2014.08.006 | - |
dc.identifier.citation | Phytochemistry. Oxford: Pergamon-elsevier Science Ltd, v. 107, p. 91-96, 2014. | - |
dc.identifier.issn | 0031-9422 | - |
dc.identifier.uri | http://hdl.handle.net/11449/116707 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/116707 | - |
dc.description.abstract | A cyclic peptide, jatrophidin I, was isolated from the latex of Jatropha curcas L. Its structure was elucidated by extensive 2D NMR spectroscopic analysis, with additional conformational studies performed using Molecular Dynamics/Simulated Annealing (MD/SA). Jatrophidin I had moderate protease inhibition activity when compared with pepstatin A; however, the peptide was inactive in antimalarial, cytotoxic and antioxidant assays. (C) 2014 Elsevier Ltd. All rights reserved. | en |
dc.description.sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | - |
dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
dc.description.sponsorship | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | - |
dc.format.extent | 91-96 | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier B.V. | - |
dc.source | Web of Science | - |
dc.subject | Jatropha curcas | en |
dc.subject | Euphorbiaceae | en |
dc.subject | Cyclic peptides | en |
dc.subject | Protease inhibition activity | en |
dc.title | Jatrophidin I, a cyclic peptide from Brazilian Jatropha curcas L.: Isolation, characterization, conformational studies and biological activity | en |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.contributor.institution | Univ Fed Rio Grande do Sul | - |
dc.contributor.institution | Univ Paris 06 | - |
dc.contributor.institution | Univ Fed Ceara | - |
dc.description.affiliation | Univ Estadual Paulista, Inst Quim, Dept Quim Organ, Nucle Bioensaios Biossintese & Ecofisiol Prod Nat, BR-14801970 Araraquara, SP, Brazil | - |
dc.description.affiliation | Univ Fed Rio Grande do Sul, Ctr Biotecnol, BR-91500970 Porto Alegre, RS, Brazil | - |
dc.description.affiliation | Univ Paris 06, Univ Paris 04, UR4, F-75252 Paris 05, France | - |
dc.description.affiliation | Univ Fed Rio Grande do Sul, Fac Farm, BR-90610000 Porto Alegre, RS, Brazil | - |
dc.description.affiliation | Univ Fed Ceara, Dept Fisiol & Farmacol, BR-60430270 Fortaleza, Ceara, Brazil | - |
dc.description.affiliation | Univ Estadual Paulista, Inst Quim, Dept Bioquim & Biotecnol, BR-14801970 Araraquara, SP, Brazil | - |
dc.description.affiliationUnesp | Univ Estadual Paulista, Inst Quim, Dept Quim Organ, Nucle Bioensaios Biossintese & Ecofisiol Prod Nat, BR-14801970 Araraquara, SP, Brazil | - |
dc.description.affiliationUnesp | Univ Estadual Paulista, Inst Quim, Dept Bioquim & Biotecnol, BR-14801970 Araraquara, SP, Brazil | - |
dc.description.sponsorshipId | CNPq: 13/07600 | - |
dc.identifier.doi | 10.1016/j.phytochem.2014.08.006 | - |
dc.identifier.wos | WOS:000343840500010 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Phytochemistry | - |
dc.identifier.orcid | 0000-0002-4767-0904 | pt |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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