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dc.contributor.authorFlorence, G.-
dc.contributor.authorKurths, J.-
dc.contributor.authorMachado, B. S.-
dc.contributor.authorFonoff, E. T.-
dc.contributor.authorCerdeira, H. A.-
dc.contributor.authorTeixeira, M. J.-
dc.contributor.authorSameshima, K.-
dc.date.accessioned2015-03-18T15:55:32Z-
dc.date.accessioned2016-10-25T20:34:47Z-
dc.date.available2015-03-18T15:55:32Z-
dc.date.available2016-10-25T20:34:47Z-
dc.date.issued2014-12-01-
dc.identifierhttp://dx.doi.org/10.1140/epjst/e2014-02304-x-
dc.identifier.citationEuropean Physical Journal-special Topics. Heidelberg: Springer Heidelberg, v. 223, n. 13, p. 2913-2922, 2014.-
dc.identifier.issn1951-6355-
dc.identifier.urihttp://hdl.handle.net/11449/117203-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/117203-
dc.description.abstractIn experimental studies, electrical stimulation (ES) has been applied to induce neuronal activity or to disrupt pathological patterns. Nevertheless, the underlying mechanisms of these activity pattern transitions are not clear. To study these phenomena, we simulated a model of the hippocampal region CA1. The computational simulations using different amplitude levels and duration of ES revealed three states of neuronal excitability: burst-firing mode, depolarization block and spreading depression wave. We used the bifurcation theory to analyse the interference of ES in the cellular excitability and the neuronal dynamics. Understanding this process would help to improve the ES techniques to control some neurological disorders.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipUNIEMP-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.format.extent2913-2922-
dc.language.isoeng-
dc.publisherSpringer-
dc.sourceWeb of Science-
dc.titleNeuronal excitability level transition induced by electrical stimulationen
dc.typeoutro-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionHumboldt Univ-
dc.contributor.institutionPotsdam Inst Climate Impact Res-
dc.contributor.institutionHosp Israelita Albert Einstein-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniv Sao Paulo, Sch Med, Dept Radiol & Oncol, LIM 43, Sao Paulo, Brazil-
dc.description.affiliationUniv Sao Paulo, Sch Med, Dept Neurol, LIM 43, Sao Paulo, Brazil-
dc.description.affiliationHumboldt Univ, Inst Phys, D-10099 Berlin, Germany-
dc.description.affiliationPotsdam Inst Climate Impact Res, Potsdam, Germany-
dc.description.affiliationHosp Israelita Albert Einstein, Inst Brain, Sao Paulo, Brazil-
dc.description.affiliationUniv Estadual Paulista, Inst Fis Teor, BR-01405 Sao Paulo, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, Inst Fis Teor, BR-01405 Sao Paulo, Brazil-
dc.description.sponsorshipIdFAPESP: 11/21138-5-
dc.description.sponsorshipIdCNPq: 309381/2012-6-
dc.identifier.doi10.1140/epjst/e2014-02304-x-
dc.identifier.wosWOS:000346248900022-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofEuropean Physical Journal-special Topics-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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