Please use this identifier to cite or link to this item:
http://acervodigital.unesp.br/handle/11449/11789
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Moris, D. V. | - |
dc.contributor.author | Melhem, M. S. C. | - |
dc.contributor.author | Martins, M. A. | - |
dc.contributor.author | Souza, L. R. | - |
dc.contributor.author | Kacew, S. | - |
dc.contributor.author | Szeszs, M. W. | - |
dc.contributor.author | Carvalho, L. R. | - |
dc.contributor.author | Pimenta-Rodrigues, M. V. | - |
dc.contributor.author | Berghs, H. A. M. | - |
dc.contributor.author | Mendes, Rinaldo Poncio | - |
dc.date.accessioned | 2014-05-20T13:34:25Z | - |
dc.date.accessioned | 2016-10-25T16:52:07Z | - |
dc.date.available | 2014-05-20T13:34:25Z | - |
dc.date.available | 2016-10-25T16:52:07Z | - |
dc.date.issued | 2012-12-01 | - |
dc.identifier | http://dx.doi.org/10.1099/jmm.0.045112-0 | - |
dc.identifier.citation | Journal of Medical Microbiology. Reading: Soc General Microbiology, v. 61, n. 12, p. 1758-1765, 2012. | - |
dc.identifier.issn | 0022-2615 | - |
dc.identifier.uri | http://hdl.handle.net/11449/11789 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/11789 | - |
dc.description.abstract | At present, few data are available on the prevalence and antifungal susceptibility of Candida parapsilosis complex isolates from HIV-infected individuals. The C. parapsilosis complex comprises three species, C. parapsilosis sensu stricto, C. metapsilosis and C. orthopsilosis. Fifteen of 318 Candida isolates were identified as members of the C. parapsilosis complex by PCR and restriction fragment length polymorphism (RFLP). The prevalence of C. parapsilosis complex isolates was 4.7 %, 2.2 % being identified as C. parapsilosis sensu stricto and 2.5% as C. metapsilosis, while no C. orthopsilosis was isolated. This is believed to be the first study that has identified isolates of C. metapsilosis obtained from the oral cavity of HIV-infected individuals. Antifungal susceptibility tests indicated that all the isolates were susceptible to amphotericin B (AMB), fluconazole (FLC), ketoconazole (KTC), itraconazole (ITC), voriconazole (VRC) and caspofungin (CASPO). Although isolates of C. parapsilosis sensu stricto and C. metapsilosis were susceptible to FLC, isolates of C. metapsilosis showed a tendency for higher MICs (>= 1.0 mu g ml(-1)). Based upon the frequency of candidiasis and the fact that certain isolates of the C. parapsilosis complex respond differently to FLC therapy, our data may be of therapeutic relevance with respect to susceptibility and potential resistance to specific antifungal agents. Our data suggest that C. metapsilosis can be a human commensal; its importance as a pathogen has yet to be confirmed. | en |
dc.format.extent | 1758-1765 | - |
dc.language.iso | eng | - |
dc.publisher | Soc General Microbiology | - |
dc.source | Web of Science | - |
dc.title | Prevalence and antifungal susceptibility of Candida parapsilosis complex isolates collected from oral cavities of HIV-infected individuals | en |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.contributor.institution | Instituto Adolfo Lutz (IAL) | - |
dc.contributor.institution | Univ Ottawa | - |
dc.contributor.institution | Fairport Ltda | - |
dc.description.affiliation | UNESP, Fac Med Botucatu, Dept Doencas Tropicais & Diagnost Imagem, Botucatu, SP, Brazil | - |
dc.description.affiliation | Adolfo Lutz Inst, São Paulo, Brazil | - |
dc.description.affiliation | Univ Ottawa, Inst Populat Biol, Ottawa, on K1N 6N5, Canada | - |
dc.description.affiliation | UNESP, Inst Biociencias, Dept Bioestat, Botucatu, SP, Brazil | - |
dc.description.affiliation | Fairport Ltda, São Paulo, Brazil | - |
dc.description.affiliationUnesp | UNESP, Fac Med Botucatu, Dept Doencas Tropicais & Diagnost Imagem, Botucatu, SP, Brazil | - |
dc.description.affiliationUnesp | UNESP, Inst Biociencias, Dept Bioestat, Botucatu, SP, Brazil | - |
dc.identifier.doi | 10.1099/jmm.0.045112-0 | - |
dc.identifier.wos | WOS:000313086000017 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Journal of Medical Microbiology | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.