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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/122481
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dc.contributor.authorSantos, Marcelo-
dc.contributor.authorSturr, Elaine-
dc.contributor.authorMaia, Lucas Lima-
dc.contributor.authorAgostini, Lidiane Pignaton-
dc.contributor.authorPeterle, Gabriela Tonini-
dc.contributor.authorMendes, Suzanny Oliveira-
dc.contributor.authorSilva, Eloiza Helena Tajara da-
dc.contributor.authorCarvalho, Marcos Brasilino-
dc.contributor.authorLouro, Iúri Drumond-
dc.contributor.authorSilva-Conforti, Adriana Madeira Álvares da-
dc.date.accessioned2015-04-27T11:55:47Z-
dc.date.accessioned2016-10-25T20:46:23Z-
dc.date.available2015-04-27T11:55:47Z-
dc.date.available2016-10-25T20:46:23Z-
dc.date.issued2013-
dc.identifierhttp://online.liebertpub.com/doi/abs/10.1089/gtmb.2013.0264-
dc.identifier.citationGenetic Testing and Molecular Biomarkers, v. 17, n. 11, p. 844-848, 2013.-
dc.identifier.issn1945-0265-
dc.identifier.urihttp://hdl.handle.net/11449/122481-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/122481-
dc.description.abstractInflammatory gene variants have been associated with several diseases, including cancer, diabetes, vascular diseases, neurodegenerative diseases, arthritis, and others. Therefore, determining the population genetic composition of inflammation-related genes can be useful for the determination of general risk, prognostic and therapeutic strategies to prevent or cure specific diseases. We have aimed to identify polymorphism genotype frequencies in genes related to the inflammatory response in the Brazilian population, namely, IjBL - 62AT, IjBL - 262CT, tumor necrosis factors alpha (TNFa) - 238GA, TNFa - 308GA, lymphotoxin-alpha (LTa) + 80AC, LTa + 252AG, FAS - 670AG, and FASL - 844TC, considering the white, black, and Pardo ethnicities of the Sa˜o Paulo State. Our results suggest that the Brazilian population is under a miscegenation process at the current time, since some genotypes are not in the Hardy–Weinberg equilibrium. In addition, we conclude that the Pardo ethnicity is derived from a complex mixture of ethnicities, including the native Indian population.en
dc.format.extent844-848-
dc.language.isoeng-
dc.sourceCurrículo Lattes-
dc.titleGenetic variability of inflammatory genes in the brazilian populationen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Estudos Lingüísticos e Literários, Instituto de Biociências Letras e Ciências Exatas de São José do Rio Preto, Sao Jose do Rio Preto, Rua Cristóvão Colombo, 2265 - sala 22 - Departamento de Estudos Lingüísticos e Literários, Jardim Nazareth, CEP 15054-000, SP, Brasil-
dc.description.affiliationUnespPrograma de Pós Graduação em Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil-
dc.description.affiliationUnespLaboratório de Biologia Molecular, Hospital Heliópolis, São Paulo, Brazil-
dc.description.affiliationUnespNúcleo de Gene´tica Humana e Molecular, Departamento de Cieˆncias Biolo´gicas, Universidade Federal do Espı´rito Santo, Vito´ria, Espı´rito Santo, Brazil-
dc.description.affiliationUnespDepartamento de Biologia, Universidade Federal do Espı´rito Santo, Alegre, Espı´rito Santo, Brazil-
dc.identifier.doihttp://dx.doi.org/10.1089/gtmb.2013.0264-
dc.rights.accessRightsAcesso aberto-
dc.relation.ispartofGenetic Testing and Molecular Biomarkers-
dc.identifier.lattes8102755896732025-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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