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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/123422
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dc.contributor.authorMelo, Nathalie Ferreira Silva de-
dc.contributor.authorGrillo, Renato-
dc.contributor.authorFraceto, Leonardo Fernandes-
dc.contributor.authorDias Filho, Newton Luiz-
dc.contributor.authorPaula, Eneida de-
dc.contributor.authorAraújo, Daniele Ribeiro de-
dc.contributor.authorRosa, André Henrique-
dc.date.accessioned2015-05-15T13:30:10Z-
dc.date.accessioned2016-10-25T20:48:24Z-
dc.date.available2015-05-15T13:30:10Z-
dc.date.available2016-10-25T20:48:24Z-
dc.date.issued2010-
dc.identifierhttp://quimicanova.sbq.org.br/detalhe_artigo.asp?id=5025-
dc.identifier.citationQuímica Nova, v. 33, n. 1, p. 65-69, 2010.-
dc.identifier.issn0100-4042-
dc.identifier.urihttp://hdl.handle.net/11449/123422-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/123422-
dc.description.abstractIn this paper we describe the preparation poly (L-lactide) (PLA) nanocapsules as a drug delivery system for the local anesthetic benzocaine. The characterization and in vitro release properties of the system were investigated. The characterization results showed a polydispersity index of 0.14, an average diameter of 190.1± 3 nm, zeta potential of –38.5 mV and an entrapment efficiency of 73%. The release profile of Benzocaine loaded in PLA nanocapsules showed a significant different behavior than that of the pure anesthetic in solution. This study is important to characterize a drug release system using benzocaine for application in pain treatment.en
dc.format.extent65-69-
dc.language.isopor-
dc.sourceCurrículo Lattes-
dc.subjectnanocapsulaspt
dc.subjectbenzocaínapt
dc.subjectcaracterização físico-químicapt
dc.titleDesenvolvimento e caracterização de nanocápsulas de poli(l-lactídeo) contendo benzocaínapt
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)-
dc.contributor.institutionUniversidade Federal do ABC (UFABC)-
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Engenharia Ambiental, Sorocaba, Av. Três de Março, 511, Alto da Boa Vista, CEP 18087180, SP, Brasil-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Engenharia Ambiental, Sorocaba, Av. Três de Março, 511, Alto da Boa Vista, CEP 18087180, SP, Brasil-
dc.rights.accessRightsAcesso aberto-
dc.identifier.fileISSN0100-4042-2010-33-01-65-69.pdf-
dc.relation.ispartofQuímica Nova-
dc.identifier.orcid0000-0002-2042-018Xpt
dc.identifier.lattes5228846314663888-
dc.identifier.lattes9175058122742496-
dc.identifier.lattes2188736885721242-
dc.identifier.lattes4741480538883395-
dc.identifier.lattes1509480515046572-
dc.identifier.lattes5343212477106568-
dc.identifier.lattes6434758592103771-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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