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http://acervodigital.unesp.br/handle/11449/123422
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DC Field | Value | Language |
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dc.contributor.author | Melo, Nathalie Ferreira Silva de | - |
dc.contributor.author | Grillo, Renato | - |
dc.contributor.author | Fraceto, Leonardo Fernandes | - |
dc.contributor.author | Dias Filho, Newton Luiz | - |
dc.contributor.author | Paula, Eneida de | - |
dc.contributor.author | Araújo, Daniele Ribeiro de | - |
dc.contributor.author | Rosa, André Henrique | - |
dc.date.accessioned | 2015-05-15T13:30:10Z | - |
dc.date.accessioned | 2016-10-25T20:48:24Z | - |
dc.date.available | 2015-05-15T13:30:10Z | - |
dc.date.available | 2016-10-25T20:48:24Z | - |
dc.date.issued | 2010 | - |
dc.identifier | http://quimicanova.sbq.org.br/detalhe_artigo.asp?id=5025 | - |
dc.identifier.citation | Química Nova, v. 33, n. 1, p. 65-69, 2010. | - |
dc.identifier.issn | 0100-4042 | - |
dc.identifier.uri | http://hdl.handle.net/11449/123422 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/123422 | - |
dc.description.abstract | In this paper we describe the preparation poly (L-lactide) (PLA) nanocapsules as a drug delivery system for the local anesthetic benzocaine. The characterization and in vitro release properties of the system were investigated. The characterization results showed a polydispersity index of 0.14, an average diameter of 190.1± 3 nm, zeta potential of –38.5 mV and an entrapment efficiency of 73%. The release profile of Benzocaine loaded in PLA nanocapsules showed a significant different behavior than that of the pure anesthetic in solution. This study is important to characterize a drug release system using benzocaine for application in pain treatment. | en |
dc.format.extent | 65-69 | - |
dc.language.iso | por | - |
dc.source | Currículo Lattes | - |
dc.subject | nanocapsulas | pt |
dc.subject | benzocaína | pt |
dc.subject | caracterização físico-química | pt |
dc.title | Desenvolvimento e caracterização de nanocápsulas de poli(l-lactídeo) contendo benzocaína | pt |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.contributor.institution | Universidade Estadual de Campinas (UNICAMP) | - |
dc.contributor.institution | Universidade Federal do ABC (UFABC) | - |
dc.description.affiliation | Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Engenharia Ambiental, Sorocaba, Av. Três de Março, 511, Alto da Boa Vista, CEP 18087180, SP, Brasil | - |
dc.description.affiliationUnesp | Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Engenharia Ambiental, Sorocaba, Av. Três de Março, 511, Alto da Boa Vista, CEP 18087180, SP, Brasil | - |
dc.rights.accessRights | Acesso aberto | - |
dc.identifier.file | ISSN0100-4042-2010-33-01-65-69.pdf | - |
dc.relation.ispartof | Química Nova | - |
dc.identifier.orcid | 0000-0002-2042-018X | pt |
dc.identifier.lattes | 5228846314663888 | - |
dc.identifier.lattes | 9175058122742496 | - |
dc.identifier.lattes | 2188736885721242 | - |
dc.identifier.lattes | 4741480538883395 | - |
dc.identifier.lattes | 1509480515046572 | - |
dc.identifier.lattes | 5343212477106568 | - |
dc.identifier.lattes | 6434758592103771 | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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