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dc.contributor.authorPavone, Chaine-
dc.contributor.authorPerussi, Livia Rodrigues-
dc.contributor.authorOliveira, Guilherme José Pimentel Lopes-
dc.contributor.authorScardueli, Cássio Rocha-
dc.contributor.authorCirelli, Joni Augusto-
dc.contributor.authorCerri, Paulo Sérgio-
dc.contributor.authorMarcantonio Junior, Elcio-
dc.contributor.authorSpolidorio, Luis Carlos-
dc.contributor.authorMarcantonio, Rosemary Adriana Chiérici-
dc.identifier.citationLasers in Medical Science, v. 30, n 3, p. 993-999, 2014.-
dc.description.abstractThe purpose of this study was to evaluate the influence of an erbium, chromium:yttrium–scandium–gallium–garnet (Er,Cr:YSGG) laser in the absence or presence of manual scaling and root planning (SRP) for the treatment of induced periodontitis in rats. Ligatures were placed in the subgingival region of the maxillary first molar. After a 7-day period, the ligatures were removed, and 40 rats were randomly divided into four groups (G), as follows: (GI) no treatment, (GII) scaling and root planning (SRP) with curettes, (GIII) Er,Cr:YSGG laser irradiation and (GIV) SRP with curettes followed by Er,Cr:YSGG laser irradiation. Seven and 30 days after the treatment, the animals were sacrificed and histologic, histometric and immunohistochemistry analyses were performed. All groups showed similar histopathological characteristics during the evaluation period. The histometric analysis was confirmed using Bonferroni and paired t tests. At 7 and 30 days, groups II, III and IV exhibited greater bone formation in the furcation area when compared to group I (p < 0.0001; p < 0.05). During the 7-day period, the groups irradiated with the laser (III and IV) showed a statistically larger new bone area than the group treated with SRP (II) (p < 0.01). Immunohistochemistry analysis revealed that the control group exhibited a higher expression of tartrate-resistant acid phosphatase (TRAP) and the receptor activator of nuclear factor κΒ ligand (RANKL) when compared to groups II, III and IV (p < 0.05). All treatments were able to reduce the inflammatory processes, consequently enabling the repair of periodontal tissues. The results achieved with the application of the Er,Cr:YSGG laser suggest that this laser can stimulate greater bone formation, especially over a shorter period of time.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.sourceCurrículo Lattes-
dc.subjectBone tissueen
dc.titleEffect of Er,Cr:YSGG laser application in the treatment of experimental periodontitisen
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Diagnóstico e Cirurgia, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá, 1680, Centro, CEP 14801-903, SP, Brasil-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Diagnóstico e Cirurgia, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá, 1680, Centro, CEP 14801-903, SP, Brasil-
dc.description.sponsorshipIdFAPESP: 2009/00479-9-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofLasers in Medical Science-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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