You are in the accessibility menu

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/125694
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBedran, Telma Blanca Lombardo-
dc.contributor.authorMarcantonio, Rosemary Adriana Chierici-
dc.contributor.authorSpin Neto, Rubens-
dc.contributor.authorMayer, Marcia Pinto Alves-
dc.contributor.authorGrenier, Daniel-
dc.contributor.authorSpolidorio, Luis Carlos-
dc.contributor.authorSpolidorio, Denise Palomari-
dc.date.accessioned2015-08-06T16:12:50Z-
dc.date.accessioned2016-10-25T20:53:28Z-
dc.date.available2015-08-06T16:12:50Z-
dc.date.available2016-10-25T20:53:28Z-
dc.date.issued2012-
dc.identifierhttp://www.journaloforalmicrobiology.net/index.php/jom/article/view/10123-
dc.identifier.citationJournal of Oral Microbiology, v. 4, p. 1-7, 2012.-
dc.identifier.issn2000-2297-
dc.identifier.urihttp://hdl.handle.net/11449/125694-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/125694-
dc.description.abstractBackground: Although previous studies have shown the presence of Porphyromonas endodontalis in chronic periodontitis associated with periapical lesions, the occurrence of this pathogen in diseased periodontal sites without periapical lesions has been poorly investigated. Objective: The aims of this study were to quantify P. endodontalis in patients with chronic periodontitis without periapical lesions, to evaluate the potential correlation of P. endodontalis with Porphyromonas gingivalis and Tannerella forsythia, and to evaluate the ability of periodontal treatment to reduce these pathogens. Design: Patients with generalized chronic periodontitis were selected by recording clinical attachment level (CAL), probing depth (PD), and bleeding on probing (BOP). Subgingival samples from 30 diseased nonadjacent sites (CAL ≥ 5 mm, PD between 5 and 7 mm and positive BOP) and 30 healthy nonadjacent sites (PD ≤ 3 mm and negative BOP) were collected and subjected to microbial analysis by quantitative polymerase chain reaction (qPCR) The variables of age, PD, CAL and BOP of all individuals were analyzed using the paired t-test (GrapPad Prism5®). Data of bacteria quantification were subjected to a normality test (D'Agostino-Pearson Test). For bacterial correlation analysis, the Spearman correlation was used. Results: Our results showed that diseased sites had significantly higher levels of P. endodontalis compared to healthy sites, similar to the results obtained for P. gingivalis and T. forsythia. The numbers of all bacterial species were reduced significantly after mechanical periodontal treatment. P. endodontalis was significantly correlated with the presence of T. forsythia and P. gingivalis in the diseased group. Conclusion: Our results suggest that there is a high prevalence of P. endodontalis, P. gingivalis and T. forsythia in periodontitis sites and that mechanical periodontal treatment is effective at reducing the pathogens studied.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.format.extent1-7-
dc.language.isoeng-
dc.sourceCurrículo Lattes-
dc.subjectPeriodontitisen
dc.subjectPolymerase chain reactionen
dc.subjectPorphyromonas endodontalisen
dc.subjectPorphyromonas gingivalisen
dc.subjectTannerella forsythiaen
dc.titlePorphyromonas endodontalis in chronic periodontitis: a clinical and microbiological cross-sectional studyen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionUniversité Laval-
dc.description.affiliationUniversidade de São Paulo, Departamento de Microbiologia, Instituto de Ciências Biomédicas-
dc.description.affiliationUniversité Laval, Oral Ecology Research Group, Faculty of Dentistry-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Diagnóstico e Cirurgia, Faculdade de Odontologia de Araraquara-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Fisiologia e Patologia, Faculdade de Odontologia de Araraquara-
dc.description.sponsorshipIdFAPESP: 2009/53308-7-
dc.identifier.doihttp://dx.doi.org/10.3402/jom.v4i0.10123-
dc.rights.accessRightsAcesso aberto-
dc.identifier.fileISSN2000-2297-2012-04-01-07.pdf-
dc.relation.ispartofJournal of Oral Microbiology-
dc.identifier.lattes2948162075170172-
dc.identifier.lattes3534044399884035-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.
 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.