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DC Field | Value | Language |
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dc.contributor.author | Avila, Erica Dorigatti de | - |
dc.contributor.author | Molon, Rafael Scaf de | - |
dc.contributor.author | Gonçalves, Daniela Aparecida de Godoi | - |
dc.contributor.author | Camparis, Cinara Maria | - |
dc.date.accessioned | 2015-08-06T16:13:08Z | - |
dc.date.accessioned | 2016-10-25T20:53:41Z | - |
dc.date.available | 2015-08-06T16:13:08Z | - |
dc.date.available | 2016-10-25T20:53:41Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Journal of Investigative and Clinical Dentistry, v. 5, n. 2, p.91-97, 2014. | - |
dc.identifier.issn | 2041-1618 | - |
dc.identifier.uri | http://hdl.handle.net/11449/125792 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/125792 | - |
dc.description.abstract | The aim of the current review was to investigate the relationship between levels of neuropeptide Substance P in periodontal disease and chronic pain. Substance P is a neuropeptide that is directly related with pain. In periodontal disease, it is expressed during the inflammatory process, and is one of the factors responsible for bone resorption. Studies have shown that Substance P levels are highest in the gingival crevicular fluid from sites with active periodontal disease and bone loss. The persistence of these substances could be sufficient to stimulate neurogenic inflammation in susceptible tissues, and cause pain. The scientific literature shows that Substance P expressed during periodontal disease can be a risk factor for patients with systemic inflammatory pathologies, such as chronic arthritis or rheumatoid arthritis. Additional research is needed to confirm the participation of this substance in the origin of some types of chronic pain. | en |
dc.format.extent | 91-97 | - |
dc.language.iso | eng | - |
dc.source | Currículo Lattes | - |
dc.subject | chronic pain | en |
dc.subject | neurogenic inflammation | en |
dc.subject | periodontal disease | en |
dc.subject | pro-inflammatory neuropeptide | en |
dc.subject | Substance P | en |
dc.title | Relationship between levels of neuropeptide Substance P in periodontal disease and chronic pain: a literature review | en |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.description.affiliation | Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Materiais Odontológicos e Prótese, Faculdade de Odontologia de Araraquara, Sao Paulo, Rua Humaita, 1680 - 4 andar, sala 420, Centro, CEP 14801-903, SP, Brasil | - |
dc.description.affiliationUnesp | Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Materiais Odontológicos e Prótese, Faculdade de Odontologia de Araraquara, Sao Paulo, Rua Humaita, 1680 - 4 andar, sala 420, Centro, CEP 14801-903, SP, Brasil | - |
dc.identifier.doi | http://dx.doi.org/10.1111/jicd.12087 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Journal of Investigative and Clinical Dentistry | - |
dc.identifier.lattes | 1390045185767833 | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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