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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/126022
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dc.contributor.authorCampos, Andressa Gianotti-
dc.contributor.authorCampos, Juliana Alvares Duarte Bonini-
dc.contributor.authorSanches, Daniel Soares-
dc.contributor.authorDagli, Maria Lúcia Zaidan-
dc.contributor.authorMatera, Julia Maria-
dc.date.accessioned2015-08-06T16:13:45Z-
dc.date.accessioned2016-10-25T20:54:13Z-
dc.date.available2015-08-06T16:13:45Z-
dc.date.available2016-10-25T20:54:13Z-
dc.date.issued2012-
dc.identifierhttp://www.scirp.org/Journal/PaperInformation.aspx?PaperID=25391#.Vb-hMBtVhHw-
dc.identifier.citationOpen Journal of Veterinary Medicine, v. 02, n. 04, p. 191-195, 2012.-
dc.identifier.issn2165-3356-
dc.identifier.urihttp://hdl.handle.net/11449/126022-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/126022-
dc.description.abstractFormation of new blood vessels is paramount for tumour growth and metastatic dissemination and vascular endothelial growth factor (VEGF) is one of the key regulators of this process. The purpose of this study was to evaluate the immunohistochemical expression of VEGF in 23 splenic hemangiosarcomas and 7 splenic hemangiomas in dogs. Blood tests performed previous to splenectomy were analysed for correlation with tumour VEGF expression. Results showed significantly higher VEGF expression in hemangiosarcomas than hemangiomas and lower hematocrit values and red cell count in dogs affected with malignant neoplasia (P < 0.05). These findings suggest the presence of high VEGF levels may be related to the malignant vascular proliferation seen in hemangiosarcomas.en
dc.format.extent191-195-
dc.language.isoeng-
dc.sourceCurrículo Lattes-
dc.subjectCanineen
dc.subjectSpleenen
dc.subjectAngiogenesisen
dc.subjectHemangiosarcomaen
dc.subjectImmunohistochemistryen
dc.subjectVascular endothelial growth factoren
dc.titleImmunohistochemical evaluation of vascular endothelial growth factor (VEGF) in splenic hemangiomas and hemangiosarcomas in dogsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade São Paulo (USP)-
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Odontologia Social, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá 1680, Centro, CEP 14801-385, SP, Brasil-
dc.description.affiliationDepartment of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo, Brazil.-
dc.description.affiliationDepartment of Animal Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, Brazil.-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Odontologia Social, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá 1680, Centro, CEP 14801-385, SP, Brasil-
dc.identifier.doihttp://dx.doi.org/10.4236/ojvm.2012.24030-
dc.rights.accessRightsAcesso aberto-
dc.relation.ispartofOpen Journal of Veterinary Medicine-
dc.identifier.lattes7167211040669505-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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