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http://acervodigital.unesp.br/handle/11449/126022
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DC Field | Value | Language |
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dc.contributor.author | Campos, Andressa Gianotti | - |
dc.contributor.author | Campos, Juliana Alvares Duarte Bonini | - |
dc.contributor.author | Sanches, Daniel Soares | - |
dc.contributor.author | Dagli, Maria Lúcia Zaidan | - |
dc.contributor.author | Matera, Julia Maria | - |
dc.date.accessioned | 2015-08-06T16:13:45Z | - |
dc.date.accessioned | 2016-10-25T20:54:13Z | - |
dc.date.available | 2015-08-06T16:13:45Z | - |
dc.date.available | 2016-10-25T20:54:13Z | - |
dc.date.issued | 2012 | - |
dc.identifier | http://www.scirp.org/Journal/PaperInformation.aspx?PaperID=25391#.Vb-hMBtVhHw | - |
dc.identifier.citation | Open Journal of Veterinary Medicine, v. 02, n. 04, p. 191-195, 2012. | - |
dc.identifier.issn | 2165-3356 | - |
dc.identifier.uri | http://hdl.handle.net/11449/126022 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/126022 | - |
dc.description.abstract | Formation of new blood vessels is paramount for tumour growth and metastatic dissemination and vascular endothelial growth factor (VEGF) is one of the key regulators of this process. The purpose of this study was to evaluate the immunohistochemical expression of VEGF in 23 splenic hemangiosarcomas and 7 splenic hemangiomas in dogs. Blood tests performed previous to splenectomy were analysed for correlation with tumour VEGF expression. Results showed significantly higher VEGF expression in hemangiosarcomas than hemangiomas and lower hematocrit values and red cell count in dogs affected with malignant neoplasia (P < 0.05). These findings suggest the presence of high VEGF levels may be related to the malignant vascular proliferation seen in hemangiosarcomas. | en |
dc.format.extent | 191-195 | - |
dc.language.iso | eng | - |
dc.source | Currículo Lattes | - |
dc.subject | Canine | en |
dc.subject | Spleen | en |
dc.subject | Angiogenesis | en |
dc.subject | Hemangiosarcoma | en |
dc.subject | Immunohistochemistry | en |
dc.subject | Vascular endothelial growth factor | en |
dc.title | Immunohistochemical evaluation of vascular endothelial growth factor (VEGF) in splenic hemangiomas and hemangiosarcomas in dogs | en |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.contributor.institution | Universidade São Paulo (USP) | - |
dc.description.affiliation | Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Odontologia Social, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá 1680, Centro, CEP 14801-385, SP, Brasil | - |
dc.description.affiliation | Department of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo, Brazil. | - |
dc.description.affiliation | Department of Animal Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, Brazil. | - |
dc.description.affiliationUnesp | Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Odontologia Social, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá 1680, Centro, CEP 14801-385, SP, Brasil | - |
dc.identifier.doi | http://dx.doi.org/10.4236/ojvm.2012.24030 | - |
dc.rights.accessRights | Acesso aberto | - |
dc.relation.ispartof | Open Journal of Veterinary Medicine | - |
dc.identifier.lattes | 7167211040669505 | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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