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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/127163
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dc.contributor.authorAraldi, Rodrigo Pinheiro-
dc.contributor.authorMelo, Thatiana Corrêa de-
dc.contributor.authorMendes, Thais Biude-
dc.contributor.authorDe Sá Júnior, Paulo-
dc.contributor.authorNozima, Bruno Heidi Nakano-
dc.contributor.authorIto, Eliana Tiemi-
dc.contributor.authorCarvalho, Rodrigo Franco de-
dc.contributor.authorSouza, Edislane Barreiros de-
dc.contributor.authorStocco, Rita de Cassia-
dc.date.accessioned2015-08-21T17:54:02Z-
dc.date.accessioned2016-10-25T20:56:46Z-
dc.date.available2015-08-21T17:54:02Z-
dc.date.available2016-10-25T20:56:46Z-
dc.date.issued2015-
dc.identifier.citationBiomedicine & Pharmacotherapy, v. 72, p. 74-82, 2015.-
dc.identifier.issn0753-3322-
dc.identifier.urihttp://hdl.handle.net/11449/127163-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/127163-
dc.description.abstractPhysical, chemical and biological agents can act in the DNA, resulting in mutation involved in cancer. Thus, genotoxic tests are required by regulatory agencies in order to evaluate potential risk of cancer. Among these tests, the comet assay (CA) and micronucleus assay (MNA) are the most commonly used. However, there are different protocols and recommendations already published. This is the first review, after the inclusion of CA in S2R1 guidance and OECD 489, which summarizes the main technical recommendations of both CA and MNA.pt
dc.format.extent74-82-
dc.language.isoeng-
dc.sourceCurrículo Lattes-
dc.subjectGenotoxicity testsen
dc.subjectComet assayen
dc.subjectMicronucleus assayen
dc.subjectMutagenesisen
dc.titleUsing the comet and micronucleus assays for genotoxicity studies: a reviewen
dc.typeoutro-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)-
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Ciências Biológicas, Faculdade de Ciências e Letras de Assis, Assis, Avenida Dom Antonio, 2100, Jardim Universitário, CEP 19806-900, SP, Brasil-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Ciências Biológicas, Faculdade de Ciências e Letras de Assis, Assis, Avenida Dom Antonio, 2100, Jardim Universitário, CEP 19806-900, SP, Brasil-
dc.identifier.doihttp://dx.doi.org/10.1016/j.biopha.2015.04.004-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofBiomedicine & Pharmacotherapy-
dc.identifier.lattes3892896473273324-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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