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dc.contributor.authorSanabria, Marciana-
dc.contributor.authorPessin, Alessandra-
dc.contributor.authorZanutto, Mirella Rossitto-
dc.contributor.authorPerobelli, Juliana Elaine-
dc.contributor.authorGuerra, Marina Trevizan-
dc.contributor.authorBanzato, Thais Petrochelli-
dc.contributor.authorBorges, Cibele dos Santos-
dc.contributor.authorKempinas, Wilma De Grava-
dc.date.accessioned2015-10-21T21:21:24Z-
dc.date.accessioned2016-10-25T21:09:27Z-
dc.date.available2015-10-21T21:21:24Z-
dc.date.available2016-10-25T21:09:27Z-
dc.date.issued2015-04-18-
dc.identifierhttp://www.tandfonline.com/doi/full/10.1080/15287394.2015.1010463#.VeC1OvlViko-
dc.identifier.citationJournal Of Toxicology And Environmental Health-part A-current Issues, v. 78, n. 8, p. 481-491, 2015.-
dc.identifier.issn1528-7394-
dc.identifier.urihttp://hdl.handle.net/11449/129556-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/129556-
dc.description.abstractProchloraz (PCZ) is a fungicide and androgen-receptor antagonist used worldwide in horticulture and agriculture. Pre- and perinatal exposure to this pesticide during sexual differentiation is deleterious for male offspring. Since data on the effects of PCZ on epididymal functions are scarce, and because sperm maturation occurs in this organ, the present investigation aimed to determine whether low PCZ doses administered to rats during the phase of sperm transit through the epididymis might affect the morphophysiology of this organ and sperm quality. Adult male Wistar rats were assigned to 4 different groups: 0 (control, vehicle) or 10, 15, or 30 mg/kg bw/d PCZ diluted in corn oil administered orally for 4 consecutive days. Morphofunctional parameters of the male reproductive tract, hormone concentrations, sperm evaluations, and fertility and histopathologic analysis of testis and epididymis were assessed. There were no statistically significant differences between treated and control groups in relation to all evaluated parameters. Data demonstrated show that PCZ exposure for a brief 4-d exposure and low doses did not produce reproductive toxicity or compromise sperm quality in adult rats.en
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.format.extent481-491-
dc.language.isoeng-
dc.publisherTaylor &francis Inc-
dc.sourceWeb of Science-
dc.titleAbsence of effects on the rat sperm quality after subacute exposure to low doses of fungicide prochlorazen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUNESP Univ Estadual Paulista, Inst Biosci, Dept Morphol, Lab Reprod &Dev Biol &Toxicol, Sao Paulo, Brazil-
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Inst Biosci, Dept Morphol, Lab Reprod &Dev Biol &Toxicol, Sao Paulo, Brazil-
dc.identifier.doihttp://dx.doi.org/10.1080/15287394.2015.1010463-
dc.identifier.wosWOS:000352618200001-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofJournal Of Toxicology And Environmental Health-part A-current Issues-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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