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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/130424
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dc.contributor.authorMinarelli-Gaspar, A. M.-
dc.contributor.authorSaska, S.-
dc.contributor.authorJimenez, J.-
dc.contributor.authorda Cunha, L. R.-
dc.contributor.authorBolini, Paulo Domingos André-
dc.contributor.authorLeal, C.-
dc.contributor.authorMorejon-Alonso, L.-
dc.contributor.authorCarrodeguas, R. G.-
dc.contributor.authorLopez-Bravo, A.-
dc.contributor.authorZavaglia, C. A. C.-
dc.date.accessioned2014-05-20T13:46:49Z-
dc.date.accessioned2016-10-25T21:21:07Z-
dc.date.available2014-05-20T13:46:49Z-
dc.date.available2016-10-25T21:21:07Z-
dc.date.issued2008-01-22-
dc.identifierhttp://www.scientific.net/KEM.361-363.1127-
dc.identifier.citationKey Engineering Materials, v. 361-363 II, p. 1127-1130.-
dc.identifier.issn1013-9826-
dc.identifier.urihttp://hdl.handle.net/11449/130424-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/130424-
dc.description.abstractThe biological behavior of a new bioactive material composed of calcium-deficient hydroxyapatite, octacalcium phosphate, and beta-tricalcium phosphate was investigated by in vitro indirect and direct cytotoxicity, cell adhesion and proliferation tests, and by in vivo subcutaneous and bone implantation in rats. The results of the in vitro studies showed that the material is biocompatible and no cytotoxic. Slightly poorer initial cell adhesion and lower cell proliferation than in control was observed, which were attributed to the reactivity and roughness of the material surface, In vivo results showed that the material is biodegradable and bioactive in bone tissue, but only biocompatible and partially biodegradable in soft tissue.en
dc.format.extent1127-1130-
dc.language.isoeng-
dc.publisherTrans Tech Publications Ltd-
dc.sourceScopus-
dc.subjectβ-tricalcium phosphate-
dc.subjectCalcium deficient hydroxiapatite-
dc.subjectIn vitro-
dc.subjectIn vivo-
dc.subjectOctacalcium phosphate-
dc.subjectBioactivity-
dc.subjectBone-
dc.subjectCalcium phosphate-
dc.subjectCell proliferation-
dc.subjectCytotoxicity-
dc.subjectHydroxyapatite-
dc.subjectBiomaterials-
dc.titleIn vitro and in vivo biological behavior of CDHA/OCP/β-TCP scaffolden
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionHospital Provincial de Ávila-
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)-
dc.contributor.institutionUniversidad de La Habana-
dc.description.affiliationDepto. de Morfologia Fac. de Odontologia de Araraquara UNESP, Rua Humaitá, 1680, 14.801-903 Araraquara-SP-
dc.description.affiliationUnidad de Investigación Clínica y Biopatología Experimental Hospital Provincial de Ávila, C/ Jesús del Gran Poder, 42, 05003 Ávila-
dc.description.affiliationDepto. de Eng. de Materiais Fac. de Eng. Mecânica UNICAMP, R. Mendeleiev s/n, CP 6122, 13.083-970 Campinas-SP-
dc.description.affiliationCentro de Biomateriales Universidad de La Habana, Ave. Universidad s/n e/ G y Ronda, 10400 La Habana-
dc.description.affiliationUnespDepto. de Morfologia Fac. de Odontologia de Araraquara UNESP, Rua Humaitá, 1680, 14.801-903 Araraquara-SP-
dc.identifier.doihttp://dx.doi.org/10.4028/www.scientific.net/KEM.361-363.1127-
dc.identifier.wosWOS:000253480200278-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofKey Engineering Materials-
dc.identifier.scopus2-s2.0-38149111869-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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