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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/131040
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dc.contributor.authorCampos, C. B.-
dc.contributor.authorMarques, T. M.-
dc.contributor.authorPereira, R. W.-
dc.contributor.authorSandrim, V. C.-
dc.date.accessioned2015-12-07T15:31:05Z-
dc.date.accessioned2016-10-25T21:22:35Z-
dc.date.available2015-12-07T15:31:05Z-
dc.date.available2016-10-25T21:22:35Z-
dc.date.issued2014-
dc.identifierhttp://dx.doi.org/10.1016/j.preghy.2013.10.002-
dc.identifier.citationPregnancy Hypertension, v. 4, n. 1, p. 11-13, 2014.-
dc.identifier.issn2210-7797-
dc.identifier.urihttp://hdl.handle.net/11449/131040-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/131040-
dc.description.abstractMicroRNAs (miRs) are small noncoding RNAs, highly stable in plasma, that regulate gene expression by base-pairing to the 3'-untranslated region of target mRNAs. We compared the expression of 3 circulating miRs (miR-125b, miR-146a, and miR-196b), which is related to the control of cell proliferation, differentiation, and apoptosis in preeclamptic (n=19) and healthy pregnant women (n=14). We found that women with preeclampsia (PE) presented lower expression of miR-196b (-2.9-fold change). The other miRs were at similar levels. This study is the first to demonstrate this difference, and highlights new opportunities for investigation into the role of miRs in PE.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)-
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.format.extent11-13-
dc.language.isoeng-
dc.publisherElsevier B. V.-
dc.sourcePubMed-
dc.subjectCirculating micrornaen
dc.subjectPreeclampsiaen
dc.subjectMir-196ben
dc.titleReduced circulating miR-196b levels is associated with preeclampsiaen
dc.typeoutro-
dc.contributor.institutionSanta Casa de Belo Horizonte-
dc.contributor.institutionUniversidade Católica de Brasília-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationNúcleo de Pós-Graduação e Pesquisa, Santa Casa de Belo Horizonte, Rua Domingos Vieira 590, Belo Horizonte, MG, Brazil-
dc.description.affiliationPrograma de Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, SGAN 916, Asa Norte, Brasília, DF 70790-160, Brazil-
dc.description.affiliationNúcleo de Pós-Graduação e Pesquisa, Santa Casa de Belo Horizonte, Rua Domingos Vieira 590, Belo Horizonte, MG, Brazil-
dc.description.affiliationUnespNúcleo de Pós-Graduação e Pesquisa, Santa Casa de Belo Horizonte, Rua Domingos Vieira 590, Belo Horizonte, MG, Brazil-
dc.identifier.doi10.1016/j.preghy.2013.10.002-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofPregnancy Hypertension-
dc.identifier.pubmed26104247-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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