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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/131559
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dc.contributor.authorKondo, Karina Yuri-
dc.contributor.authorBuzalaf, Marília Afonso Rabelo-
dc.contributor.authorManarelli, Michele Mauricio-
dc.contributor.authorDelbem, Alberto Carlos Botazzo-
dc.contributor.authorPessan, Juliano Pelim-
dc.date.accessioned2015-12-07T15:37:35Z-
dc.date.accessioned2016-10-25T21:23:49Z-
dc.date.available2015-12-07T15:37:35Z-
dc.date.available2016-10-25T21:23:49Z-
dc.date.issued2015-09-04-
dc.identifierhttp://dx.doi.org/10.1007/s00784-015-1583-4-
dc.identifier.citationClinical Oral Investigations, 2015.-
dc.identifier.issn1436-3771-
dc.identifier.urihttp://hdl.handle.net/11449/131559-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/131559-
dc.description.abstractAcidic dentifrices have been shown to be more effective than neutral ones against dental caries using in vitro, in situ, and clinical protocols. Given the scarcity of studies assessing intraoral fluoride (F) retention after using such formulations, the present study evaluated the influence of pH and F concentration of dentifrices on F uptake by saliva, biofilm, and biofilm fluid. Volunteers (n = 22) were randomly assigned to dentifrices containing 0 (placebo), 550 (LFD, low-fluoride dentifrice), and 1100 ppm F (CD, conventional dentifrice) at pH 4.5 and 7.0 and brushed their teeth 3 times/day following a double-blind, crossover protocol. Saliva and biofilm samples were collected after 7 days of using the dentifrices, 1 and approximately 12 h after last brushing. F and calcium (Ca) analyses were performed with the inverted electrode after buffering with TISAB III and the Arsenazo III method, respectively. Data were analyzed by 3-way ANOVA, Tukey's HSD test, and Pearson's correlation coefficient (p < 0.05). F concentrations in biofilm fluid and whole biofilm 1 h after brushing with acidic F-toothpastes were higher than those related to neutral counterparts, although the differences were small and not significant; no increases were observed in salivary F concentrations influenced by dentifrice pH. Moreover, no definite trend was observed for Ca concentrations in these compartments. Dentifrice pH had some influence on F uptake by the biofilm fluid, having lesser or no impact on F uptake by the biofilm and saliva, respectively. Toothbrushing with acidic toothpastes leads to slight increases in F concentrations in the biofilm fluid when compared to neutral formulations, which may contribute to the higher anticaries effect of acidic formulations.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.format.extent1-7-
dc.language.isoeng-
dc.publisherSpringer-
dc.sourcePubMed-
dc.subjectFluorideen
dc.subjectDentifricesen
dc.subjectDental plaqueen
dc.subjectSalivaen
dc.subjectBiofilmen
dc.subjectBiofilm fluiden
dc.titleEffects of pH and fluoride concentration of dentifrices on fluoride levels in saliva, biofilm, and biofilm fluid in vivoen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationDepartamento de Odontologia Infantil e Social, Faculdade de Odontologia de Araçatuba (FOA), Universidade Estadual Paulista (UNESP), Araçatuba, SP, Brasil-
dc.description.affiliationFaculdade de Odontologia de Bauru (FOB), Universidade de São Paulo (USP), Bauru, SP, Brasil-
dc.description.affiliationUnespDepartamento de Odontologia Infantil e Social, Faculdade de Odontologia de Araçatuba (FOA), Universidade Estadual Paulista (UNESP), Araçatuba, SP, Brasil-
dc.description.sponsorshipIdFAPESP: 2008/11702-8-
dc.identifier.doi10.1007/s00784-015-1583-4-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofClinical Oral Investigations-
dc.identifier.orcid0000-0002-8159-4853pt
dc.identifier.pubmed26340981-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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