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DC Field | Value | Language |
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dc.contributor.author | Megid, Jane | - |
dc.contributor.author | Kaneno, Ramon | - |
dc.date.accessioned | 2014-05-20T13:38:11Z | - |
dc.date.accessioned | 2016-10-25T16:54:32Z | - |
dc.date.available | 2014-05-20T13:38:11Z | - |
dc.date.available | 2016-10-25T16:54:32Z | - |
dc.date.issued | 2000-03-01 | - |
dc.identifier | http://dx.doi.org/10.1016/S0147-9571(99)00061-2 | - |
dc.identifier.citation | Comparative Immunology Microbiology and Infectious Diseases. Oxford: Pergamon-Elsevier B.V., v. 23, n. 2, p. 91-97, 2000. | - |
dc.identifier.issn | 0147-9571 | - |
dc.identifier.uri | http://hdl.handle.net/11449/13249 | - |
dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/13249 | - |
dc.description.abstract | The natural killer (NK) activity and lethality were evaluated in swiss mice experimentally infected with street rabies virus and submitted to immunomodulation by P. acnes (formerly Corynebacterium parvum). The infected animals were sacrificed at different times and spleen non-adherent cells were obtained through ficoll-hypaque gradient and depletion of glass-adherent cells. Immunosuppression was observed in rabies virus infected mice correlated with lower NK activity in clinically ill animals. Higher NK activity and percentual of survival were observed in the group submitted to P. acnes. The increased survival correlated with higher NK activity induced by P. acnes suggests a protective role of this natural barrier against rabies virus infection in mice. (C) 2000 Elsevier B.V. Ltd. All rights reserved. | en |
dc.format.extent | 91-97 | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier B.V. | - |
dc.source | Web of Science | - |
dc.subject | rabies | pt |
dc.subject | natural killer cells | pt |
dc.subject | immunomodulator | pt |
dc.subject | Propionibacterium acnes | pt |
dc.title | Natural killer activity in mice infected with rabies virus and submitted to P-acnes (Propionibacterium acnes) as immunomodulator | en |
dc.type | outro | - |
dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
dc.description.affiliation | UNESP, Fac Med Vet, Dept Vet Hyg & Publ Hlth, BR-18618000 Botucatu, SP, Brazil | - |
dc.description.affiliation | UNESP, Dept Microbiol & Immunol, Inst Biol Sci, BR-18618000 Botucatu, SP, Brazil | - |
dc.description.affiliationUnesp | UNESP, Fac Med Vet, Dept Vet Hyg & Publ Hlth, BR-18618000 Botucatu, SP, Brazil | - |
dc.description.affiliationUnesp | UNESP, Dept Microbiol & Immunol, Inst Biol Sci, BR-18618000 Botucatu, SP, Brazil | - |
dc.identifier.doi | 10.1016/S0147-9571(99)00061-2 | - |
dc.identifier.wos | WOS:000084770300002 | - |
dc.rights.accessRights | Acesso restrito | - |
dc.relation.ispartof | Comparative Immunology Microbiology and Infectious Diseases | - |
Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp |
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