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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/133787
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dc.contributor.authorMoreno, Andréia de Haro-
dc.contributor.authorSalgado, Hérida Regina Nunes-
dc.date.accessioned2016-01-28T16:56:36Z-
dc.date.accessioned2016-10-25T21:28:53Z-
dc.date.available2016-01-28T16:56:36Z-
dc.date.available2016-10-25T21:28:53Z-
dc.date.issued2012-
dc.identifierhttp://dx.doi.org/10.5923/j.aac.20120201.01-
dc.identifier.citationAdvances in Analytical Chemistry, v. 2, n. 1, p. 1-5, 2012.-
dc.identifier.issn2163-2847-
dc.identifier.urihttp://hdl.handle.net/11449/133787-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/133787-
dc.description.abstractStability study of ceftazidime was realized in order to investigate kinetics of degradation of this drug both in powder for injection and reconstituted sample. Ceftazidime was submitted to conditions of accelerated thermal degradation and photodegradation. Analyses of the degraded samples were performed by microbiological assay and decomposition reactions could be described by zero-order and second-order kinetics. Results obtained confirm the reliability of the microbiological assay for determination of ceftazidime by the presence of its degradation products. The present study revealed thermal and photo lability of the drug, especially as reconstituted sample, and protection is recommended during storage and handling.en
dc.description.sponsorshipFundação para o Desenvolvimento da UNESP (FUNDUNESP)-
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.format.extent1-5-
dc.language.isoeng-
dc.publisherScientific & Academic Publishing-
dc.sourceCurrículo Lattes-
dc.subjectCeftazidimeen
dc.subjectStability studiesen
dc.subjectDegradation kineticsen
dc.titleStability study and degradation kinetics of ceftazidime in pharmaceutical preparationsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Farmacos e Médicamentos, Faculdade de Ciências Farmacêuticas de Araraquara, Araraquara, Rodovia Araraquara-Jaú, km1, Campus, CEP 14801-902, SP, Brasil-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Farmacos e Médicamentos, Faculdade de Ciências Farmacêuticas de Araraquara, Araraquara, Rodovia Araraquara-Jaú, km1, Campus, CEP 14801-902, SP, Brasil-
dc.identifier.doi10.5923/j.aac.20120201.01-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofAdvances in Analytical Chemistry-
dc.identifier.lattes9881720291571774-
dc.identifier.lattes9048202968088646-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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