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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/133790
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dc.contributor.authorCazedey, Edith Cristina Laignier-
dc.contributor.authorSalgado, Hérida Regina Nunes-
dc.date.accessioned2016-01-28T16:56:37Z-
dc.date.accessioned2016-10-25T21:28:53Z-
dc.date.available2016-01-28T16:56:37Z-
dc.date.available2016-10-25T21:28:53Z-
dc.date.issued2012-
dc.identifierhttp://article.sapub.org/10.5923.j.aac.20120206.01.html-
dc.identifier.citationAdvances in Analytical Chemistry, v. 2, n. 6, p. 74-79, 2012.-
dc.identifier.issn2163-2847-
dc.identifier.urihttp://hdl.handle.net/11449/133790-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/133790-
dc.description.abstractFrom this study, methods for quantitative analysis were developed to determine cefuroxime sodium in the raw material and in pharmaceutical formulations. These tests included instrumental methods such as spectrophotometry in the ultraviolet, visible and infrared, high performance liquid chromatography and potentiometric determination by microbiological methods (agar diffusion and turbidimetric). The concentration range determined for each method varied greatly, which increases the usability of cefuroxime fori dentifying quality control. In spectrophotometric methods cefuroxime was determined from 5.0μg/ml to 2.0mg/mL.The microbiological methods have determined the drug concentration 30.0-120.0 μg/ml and HPLC ranged from 10.0to15.0μg/ml.The results obtained by analysis of the dosage form were compared to results obtained by analysis of the reference substance and showed significance. These methods proved to be reproducible and rapid determination of cefuroxime can be routinely used in quality control analysis.en
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.format.extent74-79-
dc.language.isoeng-
dc.publisherScientific & Academic Publishing-
dc.sourceCurrículo Lattes-
dc.subjectUV spectrophotometryen
dc.subjectQuinolonesen
dc.subjectAnalytical methoden
dc.subjectCiprofloxacin hydrochlorideen
dc.titleSpectrophotometric determination of ciprofloxacin hydrochloride in ophthalmic solutionen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Farmacos e Médicamentos, Faculdade de Ciências Farmacêuticas de Araraquara, Araraquara, Rodovia Araraquara-Jaú, km1, Campus, CEP 14801-902, SP, Brasil-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Farmacos e Médicamentos, Faculdade de Ciências Farmacêuticas de Araraquara, Araraquara, Rodovia Araraquara-Jaú, km1, Campus, CEP 14801-902, SP, Brasil-
dc.identifier.doi10.5923/j.aac.20120206.01-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofAdvances in Analytical Chemistry-
dc.identifier.lattes9881720291571774-
dc.identifier.lattes6258455310334944-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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