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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/133810
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dc.contributor.authorKogawa, Ana Carolina-
dc.contributor.authorSalgado, Hérida Regina Nunes-
dc.date.accessioned2016-01-28T16:56:42Z-
dc.date.accessioned2016-10-25T21:28:56Z-
dc.date.available2016-01-28T16:56:42Z-
dc.date.available2016-10-25T21:28:56Z-
dc.date.issued2013-
dc.identifierhttp://dx.doi.org/10.5923/j.pc.20130301.01-
dc.identifier.citationPhysical Chemistry, v. 33, n. 1, p. 1-6, 2013.-
dc.identifier.issn2167-7042-
dc.identifier.urihttp://hdl.handle.net/11449/133810-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/133810-
dc.description.abstractDarunavir is a protease inhibitor used in the treatment of HIV infection. It is a pillar of therapy cocktail for patients with this virus. This work proposed the development and validation of an infrared spectroscopy method for the determination of darunavir in tablets. The method was completely validated according to the International Conference on Harmonization guidelines, showing accuracy, precision, selectivity, robustness and linearity. It was linear over the concentration range of 1.5-3.5 mg with correlation coefficients greater than 0.9991 and limits of detection and quantification of 0.12 and 0.36 mg, respectively. The validated method is very useful to the routine quality control of darunavir, since it does not use polluting reagents, it is simple and has low-cost.en
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.description.sponsorshipFundação de Desenvolvimento da UNESP (FUNDUNESP)-
dc.format.extent1-6-
dc.language.isoeng-
dc.publisherScientific and Academic Publishing-
dc.sourceCurrículo Lattes-
dc.subjectDarunaviren
dc.subjectInfrareden
dc.subjectMethod validationen
dc.titleDevelopment and validation of infrared spectroscopy method for the determination of darunavir in tabetsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Ciências Farmacêuticas de Araraquara (FCFAR), Departamento de Fármacos e Medicamentos, Rodovia Araraquara-Jaú, km 1, Campus, CEP 14801-902, Araraquara, SP, Brasil-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Ciências Farmacêuticas de Araraquara (FCFAR), Departamento de Fármacos e Medicamentos, Rodovia Araraquara-Jaú, km 1, Campus, CEP 14801-902, Araraquara, SP, Brasil-
dc.identifier.doi10.5923/j.pc.20130301.01-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofPhysical Chemistry-
dc.identifier.lattes9881720291571774-
dc.identifier.lattes6638857912920334-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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