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dc.contributor.authorGuimarães, Igo Gomes-
dc.contributor.authorPezzato, Luiz Edivaldo-
dc.contributor.authorSantos, Vivian G.-
dc.contributor.authorOrsi, Ricardo de Oliveira-
dc.contributor.authorBarros, Margarida Maria-
dc.date.accessioned2016-04-01T18:44:01Z-
dc.date.accessioned2016-10-25T21:36:29Z-
dc.date.available2016-04-01T18:44:01Z-
dc.date.available2016-10-25T21:36:29Z-
dc.date.issued2014-
dc.identifierhttp://dx.doi.org/10.1111/are.12656-
dc.identifier.citationAquaculture Research, v. 1, p. 1-15, 2014.-
dc.identifier.issn1355-557X-
dc.identifier.urihttp://hdl.handle.net/11449/137066-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/137066-
dc.description.abstractVitamin A (vitA) is an essential nutrient that acts as an endocrine regulator of several metabolic pathways, modulating normal growth and health status of animals. Although the importance of vitA for normal haematology and immune response is well documented for higher vertebrates, there is limited information on the physiological effects of vitA on fish. Therefore, we designed a 130-day feeding trial to evaluate the effect of vitA supplementation on growth, haematology, immune function and resistance to experimental infection with Aeromonas hydrophila and cold-induced stress. A group of 320 Nile tilapia fingerlings 7.49 ± 0.19 g weight (mean ± SD) were randomly stocked into 40 250 L-aquaria and fed practical diets containing graded levels of vitA (0, 0.06, 0.12, 0.24, 0.48, 0.96, 1.92, 3.84 mg retinol (ROH) kg−1 diet. Growth, haematology, plasma protein profile and immune response were significantly affected by vitA supplementation; however, no clear protective effect of vitA supplementation on disease and cold stress resistance were observed in this study. Clinical signs of vitA deficiency were: resting and abnormal swimming behaviour, exophthalmia, haemorrhages at the base of fins and on skin, serous fluids in abdominal cavity, neutropenia, reduction in red blood cell count, haematocrit and haemoglobin evolving to high mortality rates in a short period of time. A dietary level of vitA around 1.2 mg ROH kg−1 may be required to prevent gross deficiency signs and promote proper growth and health status of Nile tilapia. VitA does not seem to have a pronounced effect on leucocyte differentiation, but clearly plays an important role on maintaining normal erythropoiesis.en
dc.format.extent1-15-
dc.language.isoeng-
dc.sourceCurrículo Lattes-
dc.subjectRetinolen
dc.subjectBurst respiratory activityen
dc.subjectPlasma proteinen
dc.subjectLeucocytesen
dc.titleVitamin A affects haematology, growth and immune response of Nile tilapia (Oreochromis niloticus, L.), but has no protective effect against bacterial challenge or cold-induced stressen
dc.typeoutro-
dc.contributor.institutionUniversidade Federal de Goiás (UFG)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationLaboratório de Pesquisa em Aquicultura, Universidade Federal de Goiás – Campus Jataí, Jataí, GO, Brazil-
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Melhoramento Zootécnico e Nutrição Animal, Faculdade de Medicina Veterinária e Zootecnia de Botucatu, Botucatu, CAIXA POSTAL 560, LAGEADO, CEP 18610000, SP, Brasil-
dc.description.affiliationUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Produção Animal, Faculdade de Medicina Veterinária e Zootecnia de Botucatu, Botucatu, CAIXA POSTAL 560, LAGEADO, CEP 18610000, SP, Brasil-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Melhoramento Zootécnico e Nutrição Animal, Faculdade de Medicina Veterinária e Zootecnia de Botucatu, Botucatu, CAIXA POSTAL 560, LAGEADO, CEP 18610000, SP, Brasil-
dc.description.affiliationUnespUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Produção Animal, Faculdade de Medicina Veterinária e Zootecnia de Botucatu, Botucatu, CAIXA POSTAL 560, LAGEADO, CEP 18610000, SP, Brasil-
dc.identifier.doi10.1111/are.12656-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofAquaculture Research-
dc.identifier.lattes9309759030087536-
dc.identifier.lattes9774332103381801-
dc.identifier.lattes3127091108100867-
dc.identifier.lattes1959358415883904-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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