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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/13851
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dc.contributor.authorRibeiro, Claudia Mello-
dc.contributor.authorCosta, Veruska Maia-
dc.contributor.authorFranchi Vasconcelos Gomes, Maria Isabel-
dc.contributor.authorGolim, Marjorie Assis-
dc.contributor.authorModolo, José Rafael-
dc.contributor.authorLangoni, Hélio-
dc.date.accessioned2014-05-20T13:39:55Z-
dc.date.accessioned2016-10-25T16:55:30Z-
dc.date.available2014-05-20T13:39:55Z-
dc.date.available2016-10-25T16:55:30Z-
dc.date.issued2011-03-01-
dc.identifierhttp://dx.doi.org/10.1016/j.cimid.2010.03.002-
dc.identifier.citationComparative Immunology Microbiology and Infectious Diseases. Oxford: Elsevier B.V., v. 34, n. 2, p. 111-114, 2011.-
dc.identifier.issn0147-9571-
dc.identifier.urihttp://hdl.handle.net/11449/13851-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/13851-
dc.description.abstractThe aim of this study was to assess the effects of a synbiotic composed of Bifidobacterium animalis and fructooligosaccharides on female rats infected with Toxoplasma gondii. Female Wistar rats, treated or not with dexamethasone, were daily supplemented with synbiotics for 21 days. After 15 days of supplementation, the rats were orally infected with 10(4) T. gondii bradyzoites. Blood samples were collected to measure the levels of IFN-gamma, IL-10 and T. gondii antibodies. All synbiotic-supplemented rats survived until the end of the experiment; however, non-supplemented dexamethasone-treated rats died between the fifth and the eighth days after T. gondii infection. Dexamethasone-treated rats supplemented with synbiotics (P < 0.05) were capable of synthesizing IFN-gamma, and this immunological response was essential to ensure their survival. In addition, brain cysts were found in one rat not supplemented with synbiotics. Results suggest that the synbiotic composed of B. animalis and fructooligosaccharides may be beneficial to toxoplasmosis control. (C) 2010 Elsevier Ltd. All rights reserved.en
dc.format.extent111-114-
dc.language.isoeng-
dc.publisherElsevier B.V.-
dc.sourceWeb of Science-
dc.subjectSynbioticsen
dc.subjectBifidobacterium animalisen
dc.subjectInterferon-gammaen
dc.subjectInterleukin-10en
dc.subjectToxoplasma gondiien
dc.titleEffects of synbiotic-based Bifidobacterium animalis in female rats experimentally infected with Toxoplasma gondiien
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationSão Paulo State Univ, Dept Vet Hyg & Publ Hlth, Fac Vet Med & Anim Sci, São Paulo, Brazil-
dc.description.affiliationSão Paulo State Univ, Dept Food Technol, Sch Agron Sci, Botucatu, SP, Brazil-
dc.description.affiliationSão Paulo State Univ, Ctr Blood, Botucatu Med Sch, Botucatu, SP, Brazil-
dc.description.affiliationUnespSão Paulo State Univ, Dept Vet Hyg & Publ Hlth, Fac Vet Med & Anim Sci, São Paulo, Brazil-
dc.description.affiliationUnespSão Paulo State Univ, Dept Food Technol, Sch Agron Sci, Botucatu, SP, Brazil-
dc.description.affiliationUnespSão Paulo State Univ, Ctr Blood, Botucatu Med Sch, Botucatu, SP, Brazil-
dc.identifier.doi10.1016/j.cimid.2010.03.002-
dc.identifier.wosWOS:000288718700003-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofComparative Immunology Microbiology and Infectious Diseases-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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