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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/15077
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dc.contributor.authorQueiroz, Thallita Pereira-
dc.contributor.authorSouza, Francisley Ávila-
dc.contributor.authorOkamoto, Roberta-
dc.contributor.authorMargonar, Rogerio-
dc.contributor.authorPereira-Filho, Valfrido Antonio-
dc.contributor.authorGarcia Júnior, Idelmo Rangel-
dc.contributor.authorVieira, Eduardo Hochuli-
dc.date.accessioned2013-09-30T18:29:27Z-
dc.date.accessioned2014-05-20T13:43:16Z-
dc.date.accessioned2016-10-25T16:57:53Z-
dc.date.available2013-09-30T18:29:27Z-
dc.date.available2014-05-20T13:43:16Z-
dc.date.available2016-10-25T16:57:53Z-
dc.date.issued2008-06-01-
dc.identifierhttp://dx.doi.org/10.1016/j.joms.2007.12.037-
dc.identifier.citationJournal of Oral and Maxillofacial Surgery. Philadelphia: W B Saunders Co-elsevier Inc, v. 66, n. 6, p. 1233-1240, 2008.-
dc.identifier.issn0278-2391-
dc.identifier.urihttp://hdl.handle.net/11449/15077-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/15077-
dc.description.abstractPurpose: This study sought to evaluate the effect of repeated implant drilling on the immediate bone-cell viability, and to evaluate drill wear by scanning electron microscopy.Materials and Methods: The tibiae of 10 rabbits were used, divided into 5 groups (G): G1 corresponded to new drills, and G2, G3, G4, and G5 corresponded to drills used 10, 20, 30, and 40 times, respectively. The animals received 10 sequential osteotomies in each tibia. The animals were euthanized immediately after the osteotomies by perfusion with 4% formaldehyde. Samples then underwent immunohistochemistry processing for ordinal qualitative analysis of osteoprotegerin (OPG), the RANK ligant (RANKL; a tumor-related necrosis factor receptor family), and osteocalcin protein immunolabels, as detected by the immunoperoxidase method and revealed with 3,3-diaminobenzidine. Drill wear and plastic deformation were analyzed by scanning electron microscopy (SEM).Results: The proteins were expressed in osteocytes of the superior bone cortical during the 40 drillings. However, in G4 and G5, a discrete increase in the expression of RANKL was observed, when compared with OPG; this increase was statistically significant in G5 (P = .016). The SEM analysis revealed major plastic deformation and drill wear in G4 and G5.Conclusion: Based on the present methodology, it may be concluded that cell viability is preserved if a less traumatic surgical protocol is used. However, the repeated use of drills alters the protein balance as of the thirtieth perforation. (C) 2008 American Association of Oral and Maxillofacial Surgeons.en
dc.format.extent1233-1240-
dc.language.isoeng-
dc.publisherW B Saunders Co-elsevier Inc-
dc.sourceWeb of Science-
dc.titleEvaluation of immediate bone-cell viability and of drill wear after implant osteotomies: Immunohistochemistry and scanning electron microscopy analysisen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionAraraquara Univ Ctr-
dc.contributor.institutionSão Paulo Dent Surg Assoc-
dc.description.affiliationSão Paulo State Univ Julio de Mesquita Filho, Dent Sch Aracatuba, Div Oral & Maxillofacial Surg, PRODOC Program,Dept Surg & Integrated Clin, São Paulo, Brazil-
dc.description.affiliationAraraquara Univ Ctr, Dent Sch Araraquara, Dept Periodontol, São Paulo, Brazil-
dc.description.affiliationAraraquara Univ Ctr, Dent Sch Araraquara, Dept Integrated Clin, São Paulo, Brazil-
dc.description.affiliationSão Paulo Dent Surg Assoc, Implantol Div, São Paulo, Brazil-
dc.description.affiliationSão Paulo State Univ Julio de Mesquita Filho, Dent Sch Araraquara, Dept Diagnost & Surg, Div Oral & Maxillofacial Surg, São Paulo, Brazil-
dc.description.affiliationUnespSão Paulo State Univ Julio de Mesquita Filho, Dent Sch Aracatuba, Div Oral & Maxillofacial Surg, PRODOC Program,Dept Surg & Integrated Clin, São Paulo, Brazil-
dc.description.affiliationUnespSão Paulo State Univ Julio de Mesquita Filho, Dent Sch Araraquara, Dept Diagnost & Surg, Div Oral & Maxillofacial Surg, São Paulo, Brazil-
dc.identifier.doi10.1016/j.joms.2007.12.037-
dc.identifier.wosWOS:000256267800020-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofJournal of Oral and Maxillofacial Surgery-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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