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Utilize este identificador para citar ou criar um link para este item: http://acervodigital.unesp.br/handle/11449/1535
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dc.contributor.authorVeneroni, G. B.-
dc.contributor.authorMeirelles, S. L.-
dc.contributor.authorGrossi, D. A.-
dc.contributor.authorGasparin, G.-
dc.contributor.authorIbelli, A. M. G.-
dc.contributor.authorTizioto, P. C.-
dc.contributor.authorOliveira, Henrique Nunes de-
dc.contributor.authorAlencar, M. M.-
dc.contributor.authorRegitano, L. C. A.-
dc.date.accessioned2014-05-20T13:13:54Z-
dc.date.available2014-05-20T13:13:54Z-
dc.date.issued2010-01-01-
dc.identifierhttp://dx.doi.org/10.4238/vol9-4gmr788-
dc.identifier.citationGenetics and Molecular Research. Ribeirao Preto: Funpec-editora, v. 9, n. 4, p. 1997-2003, 2010.-
dc.identifier.issn1676-5680-
dc.identifier.urihttp://hdl.handle.net/11449/1535-
dc.description.abstractCanchim is a composite cattle breed developed in Brazil for beef production. One of the breeding objectives is to increase fat deposition. QTLs for fat thickness and/or marbling have been reported on BTA4 and BTA14. The IGFBP3 and DDEF1 genes, mapped to BTA4 and BTA14, respectively, affect adipogenesis. We looked for SNPs in the IGFBP3 and DDEF1 genes that could be associated with backfat thickness in Canchim beef cattle. For SNP identification, sires with the highest accuracy were ranked according to expected breeding value for fat thickness; the 12 extremes (six sires with the highest and six with the lowest expected breeding value for the trait) were chosen. Six regions of the IGFBP3 and 14 regions of the DDEF1 were sequenced using the Sanger method. Nine SNPs were identified in IGFBP3 and 76 in the DDEF1. After an initial analysis, two SNPs were selected to be genotyped for the whole population; these were DDEF1g.279401A>G and IGFBP3c.4394T>C(Trp>Arg). We found a significant effect (P <= 0.05) of allele substitution on backfat thickness; however, the IGFBP3 SNP did not significantly affect this trait.en
dc.description.sponsorshipEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.format.extent1997-2003-
dc.language.isoeng-
dc.publisherFunpec-editora-
dc.sourceWeb of Science-
dc.subjectFat depositionen
dc.subjectCandidate genesen
dc.subjectSNP identificationen
dc.subjectBovineen
dc.titleProspecting candidate SNPs for backfat in Canchim beef cattleen
dc.typeoutro-
dc.contributor.institutionEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)-
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA) Pecuaria Sudeste, São Carlos, SP, Brazil-
dc.description.affiliationUniversidade Federal de São Carlos (UFSCar), Dept Genet & Evolucao, BR-13560 São Carlos, SP, Brazil-
dc.description.affiliationUniv Estadual Paulista, Dept Ciencias Exatas, Jaboticabal, SP, Brazil-
dc.description.affiliationUniv Estadual Paulista, Dept Zootecnia, Jaboticabal, SP, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, Dept Ciencias Exatas, Jaboticabal, SP, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, Dept Zootecnia, Jaboticabal, SP, Brazil-
dc.identifier.doi10.4238/vol9-4gmr788-
dc.identifier.wosWOS:000284324400001-
dc.rights.accessRightsAcesso aberto-
dc.identifier.fileWOS000284324400001.pdf-
dc.relation.ispartofGenetics and Molecular Research-
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