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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/15945
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dc.contributor.authorNajarro Dearo de Morais, Juliana Aparecida-
dc.contributor.authorTrindade-Suedam, Ivy Kiemle-
dc.contributor.authorPepato, Maria Teresa-
dc.contributor.authorMarcantonio, Elcio-
dc.contributor.authorWenzel, Ann-
dc.contributor.authorScaf, Gulnara-
dc.date.accessioned2013-09-30T18:31:44Z-
dc.date.accessioned2014-05-20T13:45:21Z-
dc.date.accessioned2016-10-25T16:59:23Z-
dc.date.available2013-09-30T18:31:44Z-
dc.date.available2014-05-20T13:45:21Z-
dc.date.available2016-10-25T16:59:23Z-
dc.date.issued2009-08-01-
dc.identifierhttp://dx.doi.org/10.1111/j.1600-0501.2009.01716.x-
dc.identifier.citationClinical Oral Implants Research. Malden: Wiley-blackwell Publishing, Inc, v. 20, n. 8, p. 796-801, 2009.-
dc.identifier.issn0905-7161-
dc.identifier.urihttp://hdl.handle.net/11449/15945-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/15945-
dc.description.abstractObjectivesTo evaluate the effect of diabetes mellitus (DM) and insulin therapy on bone density around osseointegrated dental implants by digital subtraction radiography (DSR).Material and methodsForty implants were placed in tibiae of 40 adult rats. After a healing period of 2 months, the animals were divided into four groups of 10 animals each: a 2-month control group, sacrificed at time (A), a diabetic group (D), an insulin-treated group (I) and a 4-month control group (C). During 2 months, group I received subcutaneous doses of insulin, whereas groups C and D received only saline. The animals in groups D, I and C were thereafter sacrificed. The glucose plasma levels (GPLs) were monitored throughout the experiment. Film radiographs were taken at implant surgery and on the day of sacrifice. The radiographs were digitized, and bone density in regions of osseointegration (OR) around the implants was evaluated by quantitative DSR between baseline and final images. Differences in shades of gray among the groups were assessed using ANOVA.ResultsGPLs were within normal range for groups A, C and I and higher for group D. There was a significant difference in mean gray shade values in the OR of subtraction images between groups D (122 +/- 7) and I (136 +/- 5) (P < 0.05) while there were no significant differences between control groups A (128 +/- 13) and C (134 +/- 10) and the insulin group I.ConclusionsDM impaired bone density around osseointegrated dental implant. Further, insulin therapy maintained bone density in diabetic rats.To cite this article:de Morais JAND, Trindade-Suedam IK, Pepato MT, Marcantonio E Jr, Wenzel A, Scaf G. Effect of diabetes mellitus and insulin therapy on bone density around osseointegrated dental implants: a digital subtraction radiography study in rats.Clin. Oral Impl. Res. 20, 2009; 796-801.doi: 10.1111/j.1600-0501.2009.01716.x.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.format.extent796-801-
dc.language.isoeng-
dc.publisherWiley-Blackwell Publishing, Inc-
dc.sourceWeb of Science-
dc.subjectbone densityen
dc.subjectdental implanten
dc.subjectdiabetes mellitusen
dc.subjectsubtraction radiographen
dc.titleEffect of diabetes mellitus and insulin therapy on bone density around osseointegrated dental implants: a digital subtraction radiography study in ratsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniv Aarhus-
dc.description.affiliationSão Paulo State Univ, UNESP, Araraquara Dent Sch, Dept Oral Diag & Surg, São Paulo, Brazil-
dc.description.affiliationSão Paulo State Univ, UNESP, Sch Pharmaceut Sci Araraquara, Dept Clin Anal, São Paulo, Brazil-
dc.description.affiliationUniv Aarhus, Fac Hlth Sci, Sch Dent, Dept Oral Radiol, Aarhus, Denmark-
dc.description.affiliationUnespSão Paulo State Univ, UNESP, Araraquara Dent Sch, Dept Oral Diag & Surg, São Paulo, Brazil-
dc.description.affiliationUnespSão Paulo State Univ, UNESP, Sch Pharmaceut Sci Araraquara, Dept Clin Anal, São Paulo, Brazil-
dc.description.sponsorshipIdFAPESP: 04/07873-0-
dc.identifier.doi10.1111/j.1600-0501.2009.01716.x-
dc.identifier.wosWOS:000267743300009-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofClinical Oral Implants Research-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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