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dc.contributor.authorSaad, W. A.-
dc.contributor.authorCamargo, LAD-
dc.contributor.authorAntunes-Rodrigues, J.-
dc.contributor.authorSimoes, S.-
dc.date.accessioned2014-05-20T13:45:41Z-
dc.date.accessioned2016-10-25T16:59:39Z-
dc.date.available2014-05-20T13:45:41Z-
dc.date.available2016-10-25T16:59:39Z-
dc.date.issued1998-09-15-
dc.identifierhttp://dx.doi.org/10.1016/S0361-9230(98)00057-4-
dc.identifier.citationBrain Research Bulletin. Oxford: Pergamon-Elsevier B.V., v. 47, n. 2, p. 163-169, 1998.-
dc.identifier.issn0361-9230-
dc.identifier.urihttp://hdl.handle.net/11449/16083-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/16083-
dc.description.abstractWater and sodium chloride intake was studied in male Holtzman rats weighing 250-300 g that had been subjected to electrolytic and chemical lesions of the septal area (SA). Water intake increased in animals with electrolytic lesion of the SA bilaterally from 169.37 +/- 8.55 (sham) to 214.87 +/- 23.10 ml/5 days (lesioned). Water intake decreased after ibotenic acid lesion of the SA from 229.33 +/- 27.60 to 127.33 +/- 22.84 ml/5 days. Sodium chloride intake (1.5%) increased in animals with electrolytic lesion of the SA from 10.0 +/- 1.73 to 15.5 +/- 1.95 ml/5 days after lesion. Also sodium chloride (1.5%) intake increased after ibotenic acid injection into the SA to a greater extent (from 7.83 +/- 1.25 to 14.33 +/- 1.87 ml/5 days). The results indicate that the water intake response may be due to lesions that involve cell bodies and fibers of passage and that the sodium intake response can also be induced by lesions which involve only cell bodies. Finally, these results led us to conclude that the SA uses its cell bodies and afferent bodies and fibers for processing inputs mediating water intake and salt appetite and that the cells bodies of the SA are implicated in increased water intake. (C) 1998 Elsevier B.V.en
dc.format.extent163-169-
dc.language.isoeng-
dc.publisherElsevier B.V.-
dc.sourceWeb of Science-
dc.subjectseptal areapt
dc.subjectwater and salt intakept
dc.subjectelectrolytic lesionpt
dc.subjectibotenic acid lesionpt
dc.titleEffect of electrolytic and chemical lesion by ibotenic acid of the septal area on water and salt intakeen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionUniv Taubate-
dc.description.affiliationPaulista State Univ, UNESP, Sch Dent, Dept Physiol, BR-14801903 Araraquara, SP, Brazil-
dc.description.affiliationUniv São Paulo, Sch Med, Dept Physiol, BR-14049 Ribeirao Preto, Brazil-
dc.description.affiliationUniv Taubate, Dept Dent, Taubate, Brazil-
dc.description.affiliationUnespPaulista State Univ, UNESP, Sch Dent, Dept Physiol, BR-14801903 Araraquara, SP, Brazil-
dc.identifier.doi10.1016/S0361-9230(98)00057-4-
dc.identifier.wosWOS:000076762400008-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofBrain Research Bulletin-
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