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dc.contributor.authorBraga, Valdir A.-
dc.contributor.authorColombari, Eduardo-
dc.contributor.authorJovita, Mariana G.-
dc.date.accessioned2014-05-20T13:46:04Z-
dc.date.accessioned2016-10-25T16:59:54Z-
dc.date.available2014-05-20T13:46:04Z-
dc.date.available2016-10-25T16:59:54Z-
dc.date.issued2011-08-01-
dc.identifierhttp://dx.doi.org/10.1007/s12264-011-1529-z-
dc.identifier.citationNeuroscience Bulletin. New York: Springer, v. 27, n. 4, p. 269-274, 2011.-
dc.identifier.issn1673-7067-
dc.identifier.urihttp://hdl.handle.net/11449/16266-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/16266-
dc.description.abstractThe brainstem is a major site in the central nervous system involved in the processing of the cardiovascular reflexes such as the baroreflex and the peripheral chemoreflex. The nucleus tractus solitarius and the rostral ventrolateral medulla are 2 important brainstem nuclei, and they play pivotal roles in autonomic cardiovascular regulation. Angiotensin II is one of the neurotransmitters involved in the processing of the cardiovascular reflexes within the brainstem. It is well-known that one of the mechanisms by which angiotensin II exerts its effect is via the activation of pathways that generate reactive oxygen species (ROS). In the central nervous system, ROS are reported to be involved in several pathological diseases such as hypertension, heart failure and sleep apnea. However, little is known about the role of ROS in the processing of the cardiovascular reflexes within the brainstem. The present review mainly discussed some recent findings documenting a role for ROS in the processing of the baroreflex and the peripheral chemoreflex in the brainstem.en
dc.format.extent269-274-
dc.language.isoeng-
dc.publisherSpringer-
dc.sourceWeb of Science-
dc.subjectangiotensin IIen
dc.subjectsuperoxideen
dc.subjectrostral ventrolateral medullaen
dc.subjectnucleus tractus solitariusen
dc.subjectbaroreflexen
dc.subjectperipheral chemoreflexen
dc.titleAngiotensin II-derived reactive oxygen species underpinning the processing of the cardiovascular reflexes in the medulla oblongataen
dc.typeoutro-
dc.contributor.institutionUniversidade Federal da Paraíba (UFPB)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniversidade Federal da Paraíba (UFPB), Pharmaceut Technol Lab, BR-58059900 Joao Pessoa, Paraiba, Brazil-
dc.description.affiliationSão Paulo State Univ, Dept Physiol & Pathol, UNESP, Araraquara, SP, Brazil-
dc.description.affiliationUnespSão Paulo State Univ, Dept Physiol & Pathol, UNESP, Araraquara, SP, Brazil-
dc.identifier.doi10.1007/s12264-011-1529-z-
dc.identifier.wosWOS:000295729300006-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofNeuroscience Bulletin-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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