You are in the accessibility menu

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/16338
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBoriollo, M. F. G.-
dc.contributor.authorBassi, R. C.-
dc.contributor.authordos Santos Nascimento, C. M. G.-
dc.contributor.authorFeliciano, L. M.-
dc.contributor.authorFrancisco, S. B.-
dc.contributor.authorBarros, L. M.-
dc.contributor.authorSpolidório, Luis Carlos-
dc.contributor.authorPalomari Spolidorio, D. M.-
dc.date.accessioned2014-05-20T13:46:14Z-
dc.date.accessioned2016-10-25T17:00:01Z-
dc.date.available2014-05-20T13:46:14Z-
dc.date.available2016-10-25T17:00:01Z-
dc.date.issued2009-12-01-
dc.identifierhttp://dx.doi.org/10.1111/j.1399-302X.2009.00524.x-
dc.identifier.citationOral Microbiology and Immunology. Malden: Wiley-blackwell Publishing, Inc, v. 24, n. 6, p. 437-450, 2009.-
dc.identifier.issn0902-0055-
dc.identifier.urihttp://hdl.handle.net/11449/16338-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/16338-
dc.description.abstractIntroduction:The aim of this study was to investigate the oral colonization profile of Candida albicans strains isolated from diabetic patients and their non-diabetic consorts. In addition hydrolytic enzyme activity of these isolates was analysed.Methods:The genetic diversity of C. albicans oral isolates from 52 couples was established using isoenzyme marker and cluster analysis. Hydrolytic enzyme characteristics, namely secreted aspartyl proteinases (SAPs) and phospholipases (PLs) were also analysed.Results:Simultaneous colonization by C. albicans was observed in the consorts of 12 couples (23.1%). Patterns of monoclonal and polyclonal oral colonization by C. albicans strains were identified and the coexistence of identical or highly related strains was observed in both members of eight couples. The genetic diversity observed in the total yeast population revealed four large, genetically distinct groups (A to D) and the coexistence of strains in couples or consorts conjugally unrelated. SAP and PL activity was observed in the majority of C. albicans isolates without any association to particular strain, strain clusters (highly related isolates), or clinical characteristics of the consorts (diabetic, non-diabetic, and gender).Conclusion:Possible sources of transmission and oral propagation of groups (clusters) of strains of C. albicans can occur between diabetic and non-diabetic consorts. A conjugal genotypic identity exists in most C. albicans-positive couples, that is, both consorts share identical or highly related strains; however, this identity is not couple-specific as seen by the coexistence of clusters in couples and unrelated consorts.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.format.extent437-450-
dc.language.isoeng-
dc.publisherWiley-Blackwell Publishing, Inc-
dc.sourceWeb of Science-
dc.subjectCandida albicansen
dc.subjectdiabetes mellitusen
dc.subjectmultilocus enzyme electrophoresisen
dc.subjectoral distributionen
dc.subjectsecreted aspartyl proteinasesen
dc.subjectphospholipasesen
dc.titleDistribution and hydrolytic enzyme characteristics of Candida albicans strains isolated from diabetic patients and their non-diabetic consortsen
dc.typeoutro-
dc.contributor.institutionUniv Alfenas UNIFENAS-
dc.contributor.institutionUniv Alfenas-
dc.contributor.institutionEinstein Integrated Fac-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniv Alfenas UNIFENAS, Fac Ciencias Med, Lab Genet & Biol Mol, Sch Med, BR-37130000 Alfenas, MG, Brazil-
dc.description.affiliationUniv Alfenas, Biomed Sch, Alfenas, MG, Brazil-
dc.description.affiliationEinstein Integrated Fac, Limeira Biomed Sch, Limeira, SP, Brazil-
dc.description.affiliationUniv Alfenas, Sch Dent, Alfenas, MG, Brazil-
dc.description.affiliationState Univ São Paulo, Araraquara Dent Sch, Oral Pathol & Physiol Dept, Oral Microbiol & Immunol Lab, Araraquara, SP, Brazil-
dc.description.affiliationUnespState Univ São Paulo, Araraquara Dent Sch, Oral Pathol & Physiol Dept, Oral Microbiol & Immunol Lab, Araraquara, SP, Brazil-
dc.description.sponsorshipIdFAPESP: 05/50673-5-
dc.identifier.doi10.1111/j.1399-302X.2009.00524.x-
dc.identifier.wosWOS:000270735900001-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofOral Microbiology and Immunology-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.
 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.