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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/17561
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dc.contributor.authorFontes, MRM-
dc.contributor.authorTeh, T.-
dc.contributor.authorRiell, R. D.-
dc.contributor.authorPark, S. B.-
dc.contributor.authorStandaert, R. E.-
dc.contributor.authorKobe, B.-
dc.date.accessioned2014-05-20T13:49:18Z-
dc.date.accessioned2016-10-25T17:01:49Z-
dc.date.available2014-05-20T13:49:18Z-
dc.date.available2016-10-25T17:01:49Z-
dc.date.issued2005-06-15-
dc.identifierhttp://dx.doi.org/10.1016/j.bbapap.2005.03.014-
dc.identifier.citationBiochimica Et Biophysica Acta-proteins and Proteomics. Amsterdam: Elsevier B.V., v. 1750, n. 1, p. 9-13, 2005.-
dc.identifier.issn1570-9639-
dc.identifier.urihttp://hdl.handle.net/11449/17561-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/17561-
dc.description.abstractImportin-alpha is the nuclear import receptor that recognizes cargo proteins with nuclear localization sequences (NLSs). Tile study of NLS peptidomimetics can provide a better understanding of the requirements for the molecular recognition of cargo proteins by importin-alpha, and potentially engender a large number of applications in medicine. Importin-a was crystallized with a set of six NLS peptidomimetics, and X-ray diffraction data were collected in the range 2.1-2.5 angstrom resolution. Preliminary electron density calculations show that the ligands are present in the crystals. (c) 2005 Elsevier B.V All rights reserved.en
dc.format.extent9-13-
dc.language.isoeng-
dc.publisherElsevier B.V.-
dc.sourceWeb of Science-
dc.subjectcrystallizationpt
dc.subjectX-ray crystallographypt
dc.subjectimportin-alphapt
dc.subjectkaryopherin-alphapt
dc.subjectnuclear localization sequencept
dc.subjectNLS peptidomimetic ligandpt
dc.titleCrystallization and preliminary X-ray diffraction analysis of importin-alpha acomplexed with NLS peptidomimeticsen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniv Queensland-
dc.contributor.institutionUniv Illinois-
dc.contributor.institutionSeoul Natl Univ-
dc.description.affiliationUniv Estadual Paulista Julio Mesquita Filho, Dept Fis & Biofis, Inst Biociencias, BR-18618000 Botucatu, SP, Brazil-
dc.description.affiliationUniv Queensland, Dept Biochem & Mol Biol, Inst Mol Biosci, ARC Special Res Ctr Funct & Appl Genom, Brisbane, Qld 4072, Australia-
dc.description.affiliationUniv Queensland, Cooperat Res Ctr Chron Inflammatory Dis, Brisbane, Qld 4072, Australia-
dc.description.affiliationUniv Illinois, Dept Chem, Chicago, IL USA-
dc.description.affiliationSeoul Natl Univ, Sch Chem, Seoul 151742, South Korea-
dc.description.affiliationUnespUniv Estadual Paulista Julio Mesquita Filho, Dept Fis & Biofis, Inst Biociencias, BR-18618000 Botucatu, SP, Brazil-
dc.identifier.doi10.1016/j.bbapap.2005.03.014-
dc.identifier.wosWOS:000229810800003-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofBiochimica et Biophysica Acta: Proteins and Proteomics-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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