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dc.contributor.authorMoraes, Fernando C.-
dc.contributor.authorCesarino, Ivana-
dc.contributor.authorCoelho, Dyovani-
dc.contributor.authorPedrosa, Valber A.-
dc.contributor.authorMachado, Sergio A. S.-
dc.identifier.citationElectroanalysis. Weinheim: Wiley-v C H Verlag Gmbh, v. 24, n. 5, p. 1115-1120, 2012.-
dc.description.abstractAn easy way to determine norepinephrine (NE) in biological fluid using a platinum ultramicroelectrode array (Pt-UMEAs) is described. Issues related to UME electrode surface treatment and characterizations are also addressed. At optimized experimental conditions the dynamic concentration range was 1.0 to 10.0 mu mol?L-1 with a detection limit of 40.5 nmol?L-1. The repeatability of current responses for injections of 5 mu mol?L-1 NE was evaluated to be 4.0?% (n=10). This approach obtained excellent sensitivity, a reliable calibration profile and stable electrochemical response for norepinephrine detection. The content of NE in urine samples without any preconcentration, purification, or pretreatment step, was successfully analyzed by the standard addition method using the Pt-UMEAs.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.publisherWiley-v C H Verlag Gmbh-
dc.sourceWeb of Science-
dc.subjectPlatinum ultramicroelectrode arrayen
dc.subjectBiological fluidsen
dc.titleHighly Sensitive Neurotransmitters Analysis at Platinum-Ultramicroelectrodes Arraysen
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUniv São Paulo, Inst Quim São Carlos, São Carlos, SP, Brazil-
dc.description.affiliationUNESP, Dept Chem & Biochem, Inst Biosci, Botucatu, SP, Brazil-
dc.description.affiliationUnespUNESP, Dept Chem & Biochem, Inst Biosci, Botucatu, SP, Brazil-
dc.description.sponsorshipIdFAPESP: 10/11567-3-
dc.description.sponsorshipIdFAPESP: 10/11049-2-
dc.description.sponsorshipIdFAPESP: 10/07478-5-
dc.rights.accessRightsAcesso restrito-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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