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http://acervodigital.unesp.br/handle/11449/19711Registro de metadados completo
| Campo DC | Valor | Idioma |
|---|---|---|
| dc.contributor.author | Arcuri, H. A. | - |
| dc.contributor.author | Palma, Mario Sergio | - |
| dc.date.accessioned | 2014-05-20T13:55:06Z | - |
| dc.date.accessioned | 2016-10-25T17:04:56Z | - |
| dc.date.available | 2014-05-20T13:55:06Z | - |
| dc.date.available | 2016-10-25T17:04:56Z | - |
| dc.date.issued | 2011-03-01 | - |
| dc.identifier | http://dx.doi.org/10.2174/092986711795029528 | - |
| dc.identifier.citation | Current Medicinal Chemistry. Sharjah: Bentham Science Publ Ltd, v. 18, n. 9, p. 1311-1317, 2011. | - |
| dc.identifier.issn | 0929-8673 | - |
| dc.identifier.uri | http://hdl.handle.net/11449/19711 | - |
| dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/19711 | - |
| dc.description.abstract | Tuberculosis is considered a worldwide health problem mainly due to co-infection with HIV and proliferation of multi-drug-resistant strains. The enzymes of the shikimate pathway are potential targets for the development of new therapies because they are essential for bacteria, but absent from mammals. The last step in this pathway is performed by chorismate synthase (CS), which catalyzes the conversion of 5-enolpyruvylshikimate-3-phosphate (EPSP) to chorismate. The aim of this article is to review the available information on chorismate synthase from Mycobacterium tuberculosis. | en |
| dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
| dc.description.sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | - |
| dc.description.sponsorship | INCT-TB | - |
| dc.description.sponsorship | Financiadora de Estudos e Projetos (FINEP) | - |
| dc.format.extent | 1311-1317 | - |
| dc.language.iso | eng | - |
| dc.publisher | Bentham Science Publ Ltd | - |
| dc.source | Web of Science | - |
| dc.subject | Chorismate synthase | en |
| dc.subject | Mycobacterium tuberculosis | en |
| dc.subject | shikimate pathway | en |
| dc.title | Understanding the Structure, Activity and Inhibition of Chorismate Synthase from Mycobacterium tuberculosis | en |
| dc.type | outro | - |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
| dc.contributor.institution | Universidade de São Paulo (USP) | - |
| dc.contributor.institution | Natl Inst Sci & Technol Immunol INCT III | - |
| dc.description.affiliation | São Paulo State Univ UNESP, CEIS, Dept Biol, Inst Biosci Rio Claro, BR-13506900 Rio Claro, SP, Brazil | - |
| dc.description.affiliation | HC FMUSP, INCor, Discipline Allergy & Immunol, São Paulo, Brazil | - |
| dc.description.affiliation | Natl Inst Sci & Technol Immunol INCT III, Alegre, RS, Brazil | - |
| dc.description.affiliationUnesp | São Paulo State Univ UNESP, CEIS, Dept Biol, Inst Biosci Rio Claro, BR-13506900 Rio Claro, SP, Brazil | - |
| dc.description.sponsorshipId | FAPESP: 06/57122-7 | - |
| dc.identifier.doi | 10.2174/092986711795029528 | - |
| dc.identifier.wos | WOS:000288986300006 | - |
| dc.rights.accessRights | Acesso restrito | - |
| dc.relation.ispartof | Current Medicinal Chemistry | - |
| Aparece nas coleções: | Artigos, TCCs, Teses e Dissertações da Unesp | |
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