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http://acervodigital.unesp.br/handle/11449/19830Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Saidemberg, Daniel M. | - |
| dc.contributor.author | da Silva-Filho, Luiz C. | - |
| dc.contributor.author | Cesar Tognoli, Lilian M. M. | - |
| dc.contributor.author | Tormena, Claudio F. | - |
| dc.contributor.author | Palma, Mario Sergio | - |
| dc.date.accessioned | 2014-05-20T13:55:25Z | - |
| dc.date.accessioned | 2016-10-25T17:05:10Z | - |
| dc.date.available | 2014-05-20T13:55:25Z | - |
| dc.date.available | 2016-10-25T17:05:10Z | - |
| dc.date.issued | 2010-04-01 | - |
| dc.identifier | http://dx.doi.org/10.1021/np900424t | - |
| dc.identifier.citation | Journal of Natural Products. Washington: Amer Chemical Soc, v. 73, n. 4, p. 527-531, 2010. | - |
| dc.identifier.issn | 0163-3864 | - |
| dc.identifier.uri | http://hdl.handle.net/11449/19830 | - |
| dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/19830 | - |
| dc.description.abstract | Polybioside (1) was isolated from the venom of the social wasp Polybia paulista, and its structure was assigned as 3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl 3-(1H-imidazol-4-yl)propanimidate by NMR and MS protocols. The application of polybioside in rat brain, followed by the detection of c-Fos protein expression in some brain regions, indicated the compound is neuroactive in a number of brain areas. Polybioside causes convulsions in rats, even when peripherally applied. | en |
| dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
| dc.description.sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | - |
| dc.description.sponsorship | Instituto de Investigação em Imunologia - Instituto Nacional de Ciência e Tecnologia (III-INCT) | - |
| dc.format.extent | 527-531 | - |
| dc.language.iso | eng | - |
| dc.publisher | Amer Chemical Soc | - |
| dc.source | Web of Science | - |
| dc.title | Polybioside, a Neuroactive Compound from the Venom of the Social Wasp Polybia paulista | en |
| dc.type | outro | - |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
| dc.contributor.institution | Universidade Estadual de Campinas (UNICAMP) | - |
| dc.description.affiliation | São Paulo State Univ, UNESP, Inst Biosci, Lab Struct Biol & Zoochem,Dept Biol CEIS, BR-13506900 Rio Claro, SP, Brazil | - |
| dc.description.affiliation | São Paulo State Univ, UNESP, Dept Chem, BR-17033360 São Paulo, Brazil | - |
| dc.description.affiliation | Univ Estadual Campinas, Inst Chem, UNICAMP, BR-13084971 Campinas, SP, Brazil | - |
| dc.description.affiliationUnesp | São Paulo State Univ, UNESP, Inst Biosci, Lab Struct Biol & Zoochem,Dept Biol CEIS, BR-13506900 Rio Claro, SP, Brazil | - |
| dc.description.affiliationUnesp | São Paulo State Univ, UNESP, Dept Chem, BR-17033360 São Paulo, Brazil | - |
| dc.description.sponsorshipId | FAPESP: 04/07942-2 | - |
| dc.description.sponsorshipId | FAPESP: 06/57122-6 | - |
| dc.description.sponsorshipId | CNPq: 472870/2004-1 | - |
| dc.identifier.doi | 10.1021/np900424t | - |
| dc.identifier.wos | WOS:000276950000003 | - |
| dc.rights.accessRights | Acesso restrito | - |
| dc.relation.ispartof | Journal of Natural Products | - |
| Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp | |
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