You are in the accessibility menu

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/21401
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBronzoni, Roberta V. M.-
dc.contributor.authorMadrid, Maria C. F. S.-
dc.contributor.authorDuarte, Danilo V. B.-
dc.contributor.authorPellegrini, Vanessa O. A.-
dc.contributor.authorPacca, Carolina C.-
dc.contributor.authorCarmo, Ana C. V.-
dc.contributor.authorZanelli, Cleslei Fernando-
dc.contributor.authorValentini, Sandro Roberto-
dc.contributor.authorSantacruz-Perez, Carolina-
dc.contributor.authorBarbosa, Joao A. R. G.-
dc.contributor.authorLutz, Carol S.-
dc.contributor.authorRahal, Paula-
dc.contributor.authorNogueira, Mauricio L.-
dc.date.accessioned2014-05-20T14:00:30Z-
dc.date.accessioned2016-10-25T17:08:02Z-
dc.date.available2014-05-20T14:00:30Z-
dc.date.available2016-10-25T17:08:02Z-
dc.date.issued2011-06-01-
dc.identifierhttp://dx.doi.org/10.1007/s00705-011-0927-x-
dc.identifier.citationArchives of Virology. Wien: Springer Wien, v. 156, n. 6, p. 931-938, 2011.-
dc.identifier.issn0304-8608-
dc.identifier.urihttp://hdl.handle.net/11449/21401-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/21401-
dc.description.abstractThe flavivirus NS5 protein is one of the most important proteins of the replication complex, and cellular proteins can interact with it. This study shows for the first time that the yellow fever virus (YFV) NS5 protein is able to interact with U1A, a protein involved in splicing and polyadenylation. We confirmed this interaction by GST-pulldown assay and by co-immunoprecipitation in YFV-infected cells. A region between amino acids 368 and 448 was identified as the site of interaction of the NS5 protein with U1A. This region was conserved among some flaviviruses of medical importance. The implications of this interaction for flavivirus replication are discussed.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.format.extent931-938-
dc.language.isoeng-
dc.publisherSpringer Wien-
dc.sourceWeb of Science-
dc.titleThe small nuclear ribonucleoprotein U1A interacts with NS5 from yellow fever virusen
dc.typeoutro-
dc.contributor.institutionFac Med Rio Preto-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionCtr Biol Mol Estrutural-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionUniv Med & Dent New Jersey-
dc.description.affiliationFac Med Rio Preto, Lab Pesquisa Viirol, BR-15090000 Sao Jose do Rio Preto, SP, Brazil-
dc.description.affiliationFac Med Rio Preto, Lab Pesquisa Viirol, Dept Doencas Dermatol Infecciosas & Parasitarias, BR-15090000 Sao Jose do Rio Preto, SP, Brazil-
dc.description.affiliationUniv Estadual Paulista, Inst Biociencias Letras & Ciencias Exatas, BR-15054000 Sao Jose do Rio Preto, SP, Brazil-
dc.description.affiliationUniv Estadual Paulista, Dept Ciencias Biol, Fac Ciencias Farmaceut, BR-14801902 Araraquara, Brazil-
dc.description.affiliationCtr Biol Mol Estrutural, Lab Nacl Luz, BR-6192 Campinas, SP, Brazil-
dc.description.affiliationUniv São Paulo, Dept Microbiol, Inst Ciencias Biomed 2, BR-05508900 São Paulo, Brazil-
dc.description.affiliationUniv Med & Dent New Jersey, Dept Biochem & Mol Biol, New Jersey Med Sch, Newark, NJ 07103 USA-
dc.description.affiliationUniv Med & Dent New Jersey, Grad Sch Biomed Sci, Newark, NJ 07103 USA-
dc.description.affiliationUnespUniv Estadual Paulista, Inst Biociencias Letras & Ciencias Exatas, BR-15054000 Sao Jose do Rio Preto, SP, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, Dept Ciencias Biol, Fac Ciencias Farmaceut, BR-14801902 Araraquara, Brazil-
dc.description.sponsorshipIdFAPESP: 2004/11098-
dc.description.sponsorshipIdFAPESP: 2005/03260-7-
dc.description.sponsorshipIdCNPq: 473613/2007-7-
dc.description.sponsorshipIdCNPq: 566289/2008-3-
dc.identifier.doi10.1007/s00705-011-0927-x-
dc.identifier.wosWOS:000291056700001-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofArchives of Virology-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.
Show simple item record Show full item record   View Statistics
 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.