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http://acervodigital.unesp.br/handle/11449/21547Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Belini Junior, Edis | - |
| dc.contributor.author | Cancado, Rodolfo D. | - |
| dc.contributor.author | Domingos, Claudia R. B. | - |
| dc.date.accessioned | 2014-05-20T14:00:59Z | - |
| dc.date.accessioned | 2016-10-25T17:08:19Z | - |
| dc.date.available | 2014-05-20T14:00:59Z | - |
| dc.date.available | 2016-10-25T17:08:19Z | - |
| dc.date.issued | 2010-10-01 | - |
| dc.identifier | http://dx.doi.org/10.5114/aoms.2010.17101 | - |
| dc.identifier.citation | Archives of Medical Science. Poznan: Termedia Publishing House Ltd, v. 6, n. 5, p. 822-825, 2010. | - |
| dc.identifier.issn | 1734-1922 | - |
| dc.identifier.uri | http://hdl.handle.net/11449/21547 | - |
| dc.identifier.uri | http://acervodigital.unesp.br/handle/11449/21547 | - |
| dc.description.abstract | We report a 20-year-old female with sickle cell anaemia and with an HbF concentration of 15.8%. The patient was not using hydroxyurea and was not receiving regular blood transfusions. The patient never had chronic manifestations of sickle cell anaemia, only pain crises of a mild intensity. After laboratory tests, we found that she was homozygous for HbS with the Bantu/atypical haplotype, and was heterozygous for the Xmnl site. The influence of the Xmnl site on the expression of HbF can explain the amelioration in clinical features in this haplotype association in a case of sickle cell anaemia. | en |
| dc.description.sponsorship | Brazilian Ministry of Health | - |
| dc.description.sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | - |
| dc.format.extent | 822-825 | - |
| dc.language.iso | eng | - |
| dc.publisher | Termedia Publishing House Ltd | - |
| dc.source | Web of Science | - |
| dc.subject | Sickle cell disease | en |
| dc.subject | HbF expression | en |
| dc.subject | clinical manifestation | en |
| dc.title | The Xmnl polymorphic site 5 ' to the gene G gamma in a Brazilian patient with sickle cell anaemia - fetal haemoglobin concentration, haematology and clinical features | en |
| dc.type | outro | - |
| dc.contributor.institution | Universidade Estadual Paulista (UNESP) | - |
| dc.contributor.institution | Santa Casa Med Sch | - |
| dc.description.affiliation | UNESP São Paulo State Univ, Dept Biol, BR-15054000 Sao Jose do Rio Preto, SP, Brazil | - |
| dc.description.affiliation | Santa Casa Med Sch, São Paulo, Brazil | - |
| dc.description.affiliationUnesp | UNESP São Paulo State Univ, Dept Biol, BR-15054000 Sao Jose do Rio Preto, SP, Brazil | - |
| dc.description.sponsorshipId | Brazilian Ministry of Health: MS 3072/2007 | - |
| dc.description.sponsorshipId | CNPq: 132573/2008-3 | - |
| dc.identifier.doi | 10.5114/aoms.2010.17101 | - |
| dc.identifier.wos | WOS:000283952200029 | - |
| dc.rights.accessRights | Acesso aberto | - |
| dc.relation.ispartof | Archives of Medical Science | - |
| Appears in Collections: | Artigos, TCCs, Teses e Dissertações da Unesp | |
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