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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/22085
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dc.contributor.authorMurakami, Mario T.-
dc.contributor.authorLourenzoni, Marco R.-
dc.contributor.authorArruda, Emerson Z.-
dc.contributor.authorTomaz, Marcelo A.-
dc.contributor.authorVicoti, Magno M.-
dc.contributor.authorAbrego, Jose R. B.-
dc.contributor.authorMelo, Paulo A.-
dc.contributor.authorArni, Raghuvir K.-
dc.date.accessioned2014-05-20T14:02:38Z-
dc.date.accessioned2016-10-25T17:09:15Z-
dc.date.available2014-05-20T14:02:38Z-
dc.date.available2016-10-25T17:09:15Z-
dc.date.issued2008-09-01-
dc.identifierhttp://eurekaselect.com/83229/article-
dc.identifier.citationProtein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 15, n. 9, p. 1002-1008, 2008.-
dc.identifier.issn0929-8665-
dc.identifier.urihttp://hdl.handle.net/11449/22085-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/22085-
dc.description.abstractBothropstoxin-II a calcium-dependent enzyme from Bothrops jararacussu venom causes tissue damage and several haemostatic disorders including platelet aggregation. In order to elucidate the structural determinants of its multiple pharmacological activities, we have studied the effects of suramin on Bothropstoxin-II and present details concerning the mode of binding.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.description.sponsorshipCAT/CEPID-
dc.format.extent1002-1008-
dc.language.isoeng-
dc.publisherBentham Science Publ Ltd-
dc.sourceWeb of Science-
dc.subjectphospholipases A(2)en
dc.subjectsuraminen
dc.subjectpharmacological activitiesen
dc.subjectstructural studiesen
dc.titleBiochemical and structural investigations of Bothropstoxin-II, a myotoxic Asp49 phospholipase A(2) from Bothrops jararacussu venomen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionLNLS-
dc.contributor.institutionUniversidade Federal do Rio de Janeiro (UFRJ)-
dc.contributor.institutionInstituto Butantan-
dc.description.affiliationIBILCE UNESP, Dept Phys, Ctr Struct & Mol Biol, BR-15054000 Sao Jose do Rio Preto, SP, Brazil-
dc.description.affiliationLNLS, Brazilian Synchrotron Light Lab, Ctr Struct Mol Biol, Campinas, SP, Brazil-
dc.description.affiliationUFRJ, CCS, ICB, Dept Basic & Clin Pharmacol, Rio de Janeiro, Brazil-
dc.description.affiliationInstituto Butantan, Ctr Appl Toxinol, São Paulo, Brazil-
dc.description.affiliationUnespIBILCE UNESP, Dept Phys, Ctr Struct & Mol Biol, BR-15054000 Sao Jose do Rio Preto, SP, Brazil-
dc.identifier.wosWOS:000259509800020-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofProtein and Peptide Letters-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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