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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/22091
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dc.contributor.authorSemenzim, Vinicius Ladeia-
dc.contributor.authorBasso, Glaucia Grazielli-
dc.contributor.authorSilva, Danilo Antonio da-
dc.contributor.authorVasconcellos, Adriano de-
dc.contributor.authorAgreli, Guilherme-
dc.contributor.authorMarques Lima-Oliveira, Ana Paula-
dc.contributor.authorKawasaki-Oyama, Rosa Sayoko-
dc.contributor.authorBraile, Domingo Marcolino-
dc.contributor.authorNery, Jose Geraldo-
dc.date.accessioned2014-05-20T14:02:39Z-
dc.date.accessioned2016-10-25T17:09:16Z-
dc.date.available2014-05-20T14:02:39Z-
dc.date.available2016-10-25T17:09:16Z-
dc.date.issued2011-08-05-
dc.identifierhttp://dx.doi.org/10.1002/app.33623-
dc.identifier.citationJournal of Applied Polymer Science. Hoboken: Wiley-blackwell, v. 121, n. 3, p. 1417-1423, 2011.-
dc.identifier.issn0021-8995-
dc.identifier.urihttp://hdl.handle.net/11449/22091-
dc.identifier.urihttp://acervodigital.unesp.br/handle/11449/22091-
dc.description.abstractBiodegradable polymeric microspheres can be used to deliver drugs through controlled rate and targeted processes. The drug is released from the particles by drug leaching or degradation of the polymeric matrix. Crystallinity can play a very important role in the degradation of polymeric matrixes; it can affect the drug-release rate, especially in chemoembolization. Most commercial embolic agents have a low degree of crystallinity, and the correlation between the drug-delivery rate and the degree of crystallinity is not fully understood. This study presents the appropriated synthesis conditions for the preparation of highly crystalline poly(vinyl alcohol) and poly(vinyl alcohol)/poly(vinyl acetate) microspheres and physicochemical characterizations by scanning electron microscopy, X-ray diffraction, differential scanning calorimetry, and cross-polarization/magic angle spinning nuclear magnetic resonance. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 121: 1417-1423, 2011en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.description.sponsorshipBraile BioMédica Industria, Comercio e Representacoes Limitada-
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
dc.format.extent1417-1423-
dc.language.isoeng-
dc.publisherWiley-Blackwell-
dc.sourceWeb of Science-
dc.subjectbiomaterialsen
dc.subjectNMRen
dc.subjectsynthesisen
dc.subjectX-rayen
dc.titleSynthesis and Characterization of Novel, Highly Crystalline Poly(vinyl alcohol) Microspheres for Chemoembolization Therapyen
dc.typeoutro-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionComercio & Representacoes Ltd-
dc.description.affiliationUniv Estadual Paulista, UNESP, Inst Biociencias Letras & Ciencias Exatas, Dept Fis, BR-15054000 São Paulo, Brazil-
dc.description.affiliationComercio & Representacoes Ltd, Braile Biomed Ind, Dept Pesquisa Desenvolvimento & Inovacao, BR-15091450 São Paulo, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, UNESP, Inst Biociencias Letras & Ciencias Exatas, Dept Fis, BR-15054000 São Paulo, Brazil-
dc.identifier.doi10.1002/app.33623-
dc.identifier.wosWOS:000291436600021-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofJournal of Applied Polymer Science-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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