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dc.contributor.authorJunqueira, Juliana Campos-
dc.contributor.authorMartins, Joyce da Silva-
dc.contributor.authorFaria, Raquel Lourdes-
dc.contributor.authorDias Colombo, Carlos Eduardo-
dc.contributor.authorCardoso Jorge, Antonio Olavo-
dc.identifier.citationLasers In Medical Science. Artington: Springer London Ltd, v. 24, n. 6, p. 877-884, 2009.-
dc.description.abstractThe study objective was to evaluate the effects of photodynamic therapy on buccal candidiasis in rats. After experimental candidiasis had been induced on the tongue dorsum, 72 rats were distributed into four groups according to treatment: treated with laser and methylene blue photosensitizer (L+P+); treated only with laser (L+P-); treated only with photosensitizer (L--P+); not treated with laser or photosensitizer (L-P-). The rats were killed immediately, 1 day, or 5 days after treatment, for microscopic analysis of the tongue dorsum. Observation verified that the photodynamic therapy group (L+P+) exhibited fewer epithelial alterations and a lower chronic inflammatory response than the L-P- group. The group L+P- presented more intense epithelial alterations and chronic inflammatory response than the remaining groups. The L-P+ group showed tissue lesions similar to those of the L-P- group. In conclusion, rats treated with photodynamic therapy developed more discrete candidiasis lesions than did the remaining groups.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.publisherSpringer London Ltd-
dc.sourceWeb of Science-
dc.subjectPhotodynamic therapyen
dc.subjectMethylene blueen
dc.subjectCandida albicansen
dc.titlePhotodynamic therapy for the treatment of buccal candidiasis in ratsen
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniversidade de Taubaté (UNITAU)-
dc.description.affiliationSão Paulo State Univ, Sch Dent Sao Jose Campos, Dept Biosci & Oral Diag, BR-12245000 São Paulo, Brazil-
dc.description.affiliationUniv Taubate, Dept Dent, São Paulo, Brazil-
dc.description.affiliationUnespSão Paulo State Univ, Sch Dent Sao Jose Campos, Dept Biosci & Oral Diag, BR-12245000 São Paulo, Brazil-
dc.description.sponsorshipIdFAPESP: 05/55084-8-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofLasers in Medical Science-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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