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dc.contributor.authorPrado, Renata F. D.-
dc.contributor.authorSilveira, Vanessa A. S.-
dc.contributor.authorRocha, Rosilene F. D.-
dc.contributor.authorVasconcellos, Luana M. R. D.-
dc.contributor.authorCarvalho, Yasmin R.-
dc.identifier.citationInternational Journal of Experimental Pathology. Malden: Wiley-blackwell, v. 93, n. 2, p. 139-147, 2012.-
dc.description.abstractThis study analysed the initial effects of the combination of oestrogen deficiency with a calcium-deficient diet on alveolar bone repair. Sixty-three 3-month-old female rats were either ovariectomized (OVX, n = 42) or sham-operated (SHAM, n = 21). Among the 42 ovariectomized rats, 21 received standard commercial food (OVX) and 21 received food with low calcium content (ESP). The mandibular first molars were extracted bilaterally 15 days after ovariectomy or sham surgery. The rats were weighed and killed at 7, 21 and 45 days after tooth extraction. The results were evaluated by descriptive microscopic analysis, histomorphometry of the trabecular and osteoid volume and mast cell counts. Analysis of the results indicated that trabecular volume and mast cell counts increased significantly over time, while osteoid volume decreased over time. Comparisons between the SHAM and OVX groups demonstrated no statistical differences, while comparison between the OVX and ESP groups indicated differences in trabecular volume and the number of mast cells. The data suggest that hormonal deficiency does not delay alveolar bone repair in OVX rats; however, oestrogen deficiency associated with calcium deficiency can lead to bone resorption through the activation of mast cells.en
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
dc.sourceWeb of Science-
dc.subjectbone turnoveren
dc.subjectlow calcium intakeen
dc.subjectwound healingen
dc.titleEffects of experimental osteoporosis and low calcium intake on postextraction sockets of ratsen
dc.contributor.institutionCruzeiro Super Sch ESC-
dc.contributor.institutionFac Pindamonhangaba-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationCruzeiro Super Sch ESC, Dept Physiotherapy, São Paulo, Brazil-
dc.description.affiliationFac Pindamonhangaba, Dept Anat, São Paulo, Brazil-
dc.description.affiliationSão Paulo State Univ UNESP, Sao Jose dos Campos Sch Dent, Dept Biosci & Oral Diag, São Paulo, Brazil-
dc.description.affiliationUnespSão Paulo State Univ UNESP, Sao Jose dos Campos Sch Dent, Dept Biosci & Oral Diag, São Paulo, Brazil-
dc.description.sponsorshipIdCNPq: 476143/2006-3-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofInternational Journal of Experimental Pathology-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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