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dc.contributor.authorXavier, Murilo-
dc.contributor.authorDavid, Debora Rodrigues-
dc.contributor.authorde Souza, Renato Aparecido-
dc.contributor.authorArrieiro, Arthur Nascimento-
dc.contributor.authorMiranda, Humberto-
dc.contributor.authorSantana, Eduardo Tadeu-
dc.contributor.authorSilva, Jose Antonio-
dc.contributor.authorCastillo Salgado, Miguel Angel-
dc.contributor.authorAimbire, Flavio-
dc.contributor.authorAlbertini, Regiane-
dc.identifier.citationLasers In Surgery and Medicine. Hoboken: Wiley-liss, v. 42, n. 6, p. 553-558, 2010.-
dc.description.abstractBackground and Objectives: The present study investigated the effects of low-level light emitting diode (LED) therapy (880 +/- 10 nm) on inflammatory process in a experimental model of Achilles tendinitis induced by collagenase.Study Design/Materials and Methods: Fifty-six male Wistar were separated into seven groups (n = 8), three groups in the experimental period of 7 days and four groups in the experimental period of 14 days, the control group (CONT), tendinitis group (TEND), LED therapy group (LEDT) for both experimental periods, and LED therapy group 7th to 14th day (LEDT delay) for 14 days experimental period. The LED parameters was 22 mW CW of optical output power, distributed in an irradiation area of 0.5 cm(2), with an irradiation time of 170 seconds, the applied energy density was 7.5 J/cm(2) in contact. The therapy was initiated 12 hours after the tendinitis induction, with a 48-hour interval between the irradiations. The histological analysis and inflammatory mediators were quantifiedResults: Our results showed that LED decreases the inflammatory cells influx and mRNA expression to IL-1 beta, IL-6, tumor necrosis factor-alpha (TNF-alpha) in both phase, and cyclooxygenase-2 (COX-2) just in initial phase (P < 0 05).Conclusion: Our results suggest that the anti-inflammatory therapy with low-power LED (880 nm) enhanced the tissue response in all groups We can conclude that the LED was able to reduce signs of inflammation in collagenase-induced tendinitis in rats by reducing the number of inflammatory cells and decrease mRNA expression of cytokines Lasers Surg. Med. 42:553-558, 2010 (C) 2010 Wiley-Liss, Inc.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.sourceWeb of Science-
dc.subjectcalcaneous tendonen
dc.subjecthistological analysisen
dc.subjectinflammatory mediatorsen
dc.titleAnti-Inflammatory Effects of Low-Level Light Emitting Diode Therapy on Achilles Tendinitis in Ratsen
dc.contributor.institutionVale Paraiba Univ-
dc.contributor.institutionUniv Fed Vales Jequitinhonha & Mucuri-
dc.contributor.institutionUniversidade Nove de Julho (UNINOVE)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.contributor.institutionUniv Camilo Castelo Branco-
dc.description.affiliationVale Paraiba Univ, Inst Res & Dev, IP&D, BR-12244000 São Paulo, Brazil-
dc.description.affiliationUniv Fed Vales Jequitinhonha & Mucuri, Dept Phys Therapy, BR-39100000 Diamantina, MG, Brazil-
dc.description.affiliationCtr Univ Nove de Julho, Dept Ciencias Reabilitacao, São Paulo, Brazil-
dc.description.affiliationUniv Estadual Paulista, Fac Odontol, São Paulo, Brazil-
dc.description.affiliationUniv Camilo Castelo Branco, BR-116 São Paulo, Brazil-
dc.description.affiliationUnespUniv Estadual Paulista, Fac Odontol, São Paulo, Brazil-
dc.description.sponsorshipIdFAPESP: 07/02596-7-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofLasers In Surgery and Medicine-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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