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dc.contributor.authorBorges Pereira Costa, Anna Carolina-
dc.contributor.authorCampos Rasteiro, Vanessa Maria-
dc.contributor.authorHashimoto, Emily Setsuko Halter da Silva-
dc.contributor.authorAraujo, Cassia Fernandes-
dc.contributor.authorPereira, Cristiane Aparecida-
dc.contributor.authorJunqueira, Juliana Campos-
dc.contributor.authorCardoso Jorge, Antonio Olavo-
dc.identifier.citationOral Surgery Oral Medicine Oral Pathology Oral Radiology. New York: Elsevier B.V., v. 114, n. 1, p. 67-74, 2012.-
dc.description.abstractObjective. This study evaluated the effects of photodynamic therapy (PDT) on buccal candidiasis in mice and on the adherence of yeast to buccal epithelial cells (BECs) in vitro.Study Design. A total of 56 immunosuppressed mice with buccal candidiasis were subjected to PDT, consisting of treatment with erythrosine (400 mu mol/L) followed by exposure to a green LED (14.34 J cm(-2)). After treatment, the yeasts recovered from the mice were quantified (CFU/mL) and analyzed for the effects of PDT on their adherence to BECs. The data were analyzed using ANOVA, the Tukey test, Kruskal-Wallis test and Student t test.Results. PDT significantly reduced the amount of yeast present in the lesions by 0.73 log(10) (P = .018) and reduced C. albicans adherence to BECs by 35% without damaging adjacent tissues (P = .045).Conclusions. Photodynamic therapy exhibited antifungal effects against C. albicans biofilms formed in vivo and reduced the capacity of C. albicans to adhere to BECs in vitro. (Oral Surg Oral Med Oral Pathol Oral Radiol 2012;114:67-74)en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
dc.publisherElsevier B.V.-
dc.sourceWeb of Science-
dc.titleEffect of erythrosine- and LED-mediated photodynamic therapy on buccal candidiasis infection of immunosuppressed mice and Candida albicans adherence to buccal epithelial cellsen
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationUNESP Univ Estadual Paulista, Dept Biosci & Oral Diag, Sch Dent Sao Jose dos Campos, Sao Jose Dos Campos, SP, Brazil-
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Dept Biosci & Oral Diag, Sch Dent Sao Jose dos Campos, Sao Jose Dos Campos, SP, Brazil-
dc.description.sponsorshipIdFAPESP: 09/52048-1-
dc.description.sponsorshipIdFAPESP: 10/18753-7-
dc.description.sponsorshipIdFAPESP: 09/12005-1-
dc.description.sponsorshipIdFAPESP: 10/01988-1-
dc.description.sponsorshipIdFAPESP: 10/00879-4-
dc.rights.accessRightsAcesso aberto-
dc.relation.ispartofOral Surgery Oral Medicine Oral Pathology Oral Radiology-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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